国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2015年
1期
172-173
,共2页
慢性肾功能衰竭%干眼%Schirmer试验%泪膜破裂时间%角膜荧光素染色
慢性腎功能衰竭%榦眼%Schirmer試驗%淚膜破裂時間%角膜熒光素染色
만성신공능쇠갈%간안%Schirmer시험%루막파렬시간%각막형광소염색
?KEYWORDS:chronic renal failure%dry eye%Schirmer ▏test%break - up time of tear film%corneal fluorescein staining
目的：：探讨慢性肾功能衰竭( CRF)患者出现干眼的特点及影响因素,提供临床参考方法。方法：对我院61例122眼慢性肾功能衰竭患者( CRF组),与61例健康人员(对照组)两组人员进行泪液分泌试验(Schirmer I test,SIt),泪膜破裂时间测定(BUT),角膜荧光素染色检查( FL),比较分析两组人员各项检查结果,分析CRF患者发生干眼的相关因素。结果：CRF组患者的泪液分泌试验值,泪膜破裂时间低于正常人群(P<0.05)。 CRF组泪液分泌减少( SIt<10mm/5min)的比例为49.2%(60/122)高于对照组10.0%(12/122),两组比较差异有统计学意义(X2=45.39,P<0.05)。 CRF泪膜不稳定(BUT≤10s)的比例为75.4%(92/122),高于对照组27.0%(33/122),其差异有统计学意义(X2=57.1, P<0.05)。角膜荧光染色(FL)阳性率为37.7%(46/122),高于对照组10.7%(13/122),两组差异有统计学意义(X2=24.34,P<0.05)。结论：慢性肾功能衰竭患者泪液分泌减少,泪膜稳定性下降是干眼症的易患人群,临床上应注意对CRF患者干眼的治疗。
目的：：探討慢性腎功能衰竭( CRF)患者齣現榦眼的特點及影響因素,提供臨床參攷方法。方法：對我院61例122眼慢性腎功能衰竭患者( CRF組),與61例健康人員(對照組)兩組人員進行淚液分泌試驗(Schirmer I test,SIt),淚膜破裂時間測定(BUT),角膜熒光素染色檢查( FL),比較分析兩組人員各項檢查結果,分析CRF患者髮生榦眼的相關因素。結果：CRF組患者的淚液分泌試驗值,淚膜破裂時間低于正常人群(P<0.05)。 CRF組淚液分泌減少( SIt<10mm/5min)的比例為49.2%(60/122)高于對照組10.0%(12/122),兩組比較差異有統計學意義(X2=45.39,P<0.05)。 CRF淚膜不穩定(BUT≤10s)的比例為75.4%(92/122),高于對照組27.0%(33/122),其差異有統計學意義(X2=57.1, P<0.05)。角膜熒光染色(FL)暘性率為37.7%(46/122),高于對照組10.7%(13/122),兩組差異有統計學意義(X2=24.34,P<0.05)。結論：慢性腎功能衰竭患者淚液分泌減少,淚膜穩定性下降是榦眼癥的易患人群,臨床上應註意對CRF患者榦眼的治療。
목적：：탐토만성신공능쇠갈( CRF)환자출현간안적특점급영향인소,제공림상삼고방법。방법：대아원61례122안만성신공능쇠갈환자( CRF조),여61례건강인원(대조조)량조인원진행루액분비시험(Schirmer I test,SIt),루막파렬시간측정(BUT),각막형광소염색검사( FL),비교분석량조인원각항검사결과,분석CRF환자발생간안적상관인소。결과：CRF조환자적루액분비시험치,루막파렬시간저우정상인군(P<0.05)。 CRF조루액분비감소( SIt<10mm/5min)적비례위49.2%(60/122)고우대조조10.0%(12/122),량조비교차이유통계학의의(X2=45.39,P<0.05)。 CRF루막불은정(BUT≤10s)적비례위75.4%(92/122),고우대조조27.0%(33/122),기차이유통계학의의(X2=57.1, P<0.05)。각막형광염색(FL)양성솔위37.7%(46/122),고우대조조10.7%(13/122),량조차이유통계학의의(X2=24.34,P<0.05)。결론：만성신공능쇠갈환자루액분비감소,루막은정성하강시간안증적역환인군,림상상응주의대CRF환자간안적치료。
?AlM: To investigate the clinical characteristics and influencing factors of chronic renal failure ( CRF) patients with dry eye, and to provide clinical reference.?METHODS:Sixty-one cases (122 eyes) of patients with CRF ( CRF group ) and 61 cases ( 122 eyes ) of healthy persons ( control group) were carried out on Schirmer ▏test ( S▏t ) , break-up time of tear film ( BUT ) , corneal fluorescein staining ( FL) , test results of two groups were compared and related factors of dry eye in CRF patients were analyzed.?RESULTS: The results of S▏t and BUT in CRF group were lower than that in the control group (P<0. 05). The proportion of tear secretion reduce in CRF group ( S▏t<10mm/5min) was 49. 2% ( 60/122 ), which was higher than that in the control group ( 10. 0%, 12/122 ), the difference was statistically significant ( X2 = 45. 39, P <0. 05). The percentage of instability of tear film in CRF group (BUT≤10s) was 75. 4% (92/122), which was significantly higher than that in the control group (27. 0%, 33/122) (X2=57. 1, P<0. 05). The positive rate of corneal FL was 37. 7% (46/122), which was higher than that of the control group (10. 7%, 13/122), there was a statistically significant difference (X2= 24. 34, P<0. 05).?CONCLUSlON:CRF patients with a decrease in tear film stability and tear secretion are susceptible population to dry eye, clinically should be paid attention to the treatment.
