国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2015年
1期
104-107
,共4页
中心性浆液性脉络膜视网膜病变%脉络膜%光学相干断层摄影术
中心性漿液性脈絡膜視網膜病變%脈絡膜%光學相榦斷層攝影術
중심성장액성맥락막시망막병변%맥락막%광학상간단층섭영술
?KEYWORDS:central serous chorioretinopathy%choroid%optical coherence tomography
目的：：评价利用OCT加强深度扫描模式测量中心性浆液性脉络膜视网膜病变( central serous chorioretinopathy, CSC)脉络膜厚度的意义。方法：采用回顾性病例对照研究。纳入经临床确诊的CSC患者65例65眼和年龄、性别、屈光度相匹配的正常对照组50例50眼。使用光学相干断层扫描的加强深度扫描模式( coherence tomography with enhanced depth imaging, OCT-EDI)分别测量65例患者的患眼和对侧眼,以及50例50眼正常对照者的黄斑中心凹下脉络膜厚度(subfoveal choroidal thickness,SFCT)。其中65例患者中有40例自愈,14例行光动力学( photodynamic therapy, PDT)治疗,11例行氩激光(laser photocoagulation,LP)治疗,分别测量3mo后的SFCT,与前次的比较进行统计学分析。结果：CSC患者65例的患眼和对侧眼,以及50例50眼正常对照组的SFCT测量结果分别为436.23±89.50,389.45±101.03,329.36±95.87μm。患眼和对侧眼SFCT分别与正常对照组比较,显著增加(P=0.008,P=0.013)。患眼的SFCT与对侧眼比较也有统计学差异( P=0.021)。 PDT治疗后SFCT显著性降低( P=0.032), LP治疗后和自愈者SFCT水平较前降低,但未显示出统计学差异( P=0.057 , 0.076)。结论：OCT-EDI是观察CSC脉络膜形态的有效方法,CSC患者SFCT较对侧眼和正常对照组明显增高。
目的：：評價利用OCT加彊深度掃描模式測量中心性漿液性脈絡膜視網膜病變( central serous chorioretinopathy, CSC)脈絡膜厚度的意義。方法：採用迴顧性病例對照研究。納入經臨床確診的CSC患者65例65眼和年齡、性彆、屈光度相匹配的正常對照組50例50眼。使用光學相榦斷層掃描的加彊深度掃描模式( coherence tomography with enhanced depth imaging, OCT-EDI)分彆測量65例患者的患眼和對側眼,以及50例50眼正常對照者的黃斑中心凹下脈絡膜厚度(subfoveal choroidal thickness,SFCT)。其中65例患者中有40例自愈,14例行光動力學( photodynamic therapy, PDT)治療,11例行氬激光(laser photocoagulation,LP)治療,分彆測量3mo後的SFCT,與前次的比較進行統計學分析。結果：CSC患者65例的患眼和對側眼,以及50例50眼正常對照組的SFCT測量結果分彆為436.23±89.50,389.45±101.03,329.36±95.87μm。患眼和對側眼SFCT分彆與正常對照組比較,顯著增加(P=0.008,P=0.013)。患眼的SFCT與對側眼比較也有統計學差異( P=0.021)。 PDT治療後SFCT顯著性降低( P=0.032), LP治療後和自愈者SFCT水平較前降低,但未顯示齣統計學差異( P=0.057 , 0.076)。結論：OCT-EDI是觀察CSC脈絡膜形態的有效方法,CSC患者SFCT較對側眼和正常對照組明顯增高。
목적：：평개이용OCT가강심도소묘모식측량중심성장액성맥락막시망막병변( central serous chorioretinopathy, CSC)맥락막후도적의의。방법：채용회고성병례대조연구。납입경림상학진적CSC환자65례65안화년령、성별、굴광도상필배적정상대조조50례50안。사용광학상간단층소묘적가강심도소묘모식( coherence tomography with enhanced depth imaging, OCT-EDI)분별측량65례환자적환안화대측안,이급50례50안정상대조자적황반중심요하맥락막후도(subfoveal choroidal thickness,SFCT)。기중65례환자중유40례자유,14례행광동역학( photodynamic therapy, PDT)치료,11례행아격광(laser photocoagulation,LP)치료,분별측량3mo후적SFCT,여전차적비교진행통계학분석。결과：CSC환자65례적환안화대측안,이급50례50안정상대조조적SFCT측량결과분별위436.23±89.50,389.45±101.03,329.36±95.87μm。환안화대측안SFCT분별여정상대조조비교,현저증가(P=0.008,P=0.013)。환안적SFCT여대측안비교야유통계학차이( P=0.021)。 PDT치료후SFCT현저성강저( P=0.032), LP치료후화자유자SFCT수평교전강저,단미현시출통계학차이( P=0.057 , 0.076)。결론：OCT-EDI시관찰CSC맥락막형태적유효방법,CSC환자SFCT교대측안화정상대조조명현증고。
Abstract? AlM: To evaluate the meaning of using optical coherence tomography with enhanced depth imaging ( OCT-EDl ) to measure choroidal thickness of central serous retinopathy ( CSC) .?METHODS: With the retrospective case control study, 65 patients (65 eyes) with CSC and 50 healthy controls (50 eyes ) with age, gender and diopter - matched were recruited in this study. OCT-EDl were used to measure the subfoveal choroidal thickness ( SFCT ) in CSC eyes, the fellow eyes and also the control eyes. Of which 40 of the 65 CSC patients self-cured, 14 of them were treated with photodynamic therapy ( PDT ) , the left 11 accepted the laser photocoagulation ( LP ) . SFCT were measured 3mo after that. Compared with the previous data, the statistical analysis was carried out.?RESULTS: The SFCT value of 65 CSC eyes, 65 fellow eyes and 50 control eyes were 436. 23 ± 89. 50, 389. 45 ± 101. 03 and 329. 36 ± 95. 87μm, respectively. The SFCT of suffer and fellow eyes increased significantly compared to the control eyes ( P = 0. 008 and 0. 013, respectively). There was also significant difference in SFCT between the CSC eyes and the fellow eyes (P=0. 021). The SFCT were significantly decreased after PDT (P=0. 032), but with no significant changes after LP or self-cured ( P=0. 057 and 0. 076, respectively).?CONCLUSlON: OCT-EDl is a useful method to assess the choroidal topographic changes of CSC. The SFCT are significantly increased in the CSC eyes compared with that in the fellow eyes and the control eyes.
