国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2015年
1期
101-103
,共3页
张锡钢%吴萍%童颖%栗印兰
張錫鋼%吳萍%童穎%慄印蘭
장석강%오평%동영%률인란
视网膜静脉阻塞%丹参注射液%离子导入%蚓激酶
視網膜靜脈阻塞%丹參註射液%離子導入%蚓激酶
시망막정맥조새%단삼주사액%리자도입%인격매
?KEYWORDS:retinal vein occlusion%Danshen injection%iontophoresis%lumbrokinase
目的：：探讨丹参注射液离子导入配合蚓激酶治疗早期视网膜静脉阻塞患者的临床效果,并观察其预后,为临床提供客观依据。方法：随机选择本院2011-01/2014-04收治的早期RVO患者82例117眼,对照组41例59眼,应用蚓激酶治疗；观察组41例58眼,应用丹参注射液离子导入配合蚓激酶治疗。主要观察指标为治疗效果、观察患者视力恢复情况及视网膜循环时间等指标。结果：观察组总有效率为85.4%(35/41),高于对照组68.3%(28/41),差异有统计学意义(P<0.05)；观察组无效率为14.6%(6/41),低于对照组31.7%(13/41),差异有统计学意义(P<0.05)；观察组视力恢复4.8~5.0为53.7%(22/41),高于对照组41.5%(17/41),差异有统计学意义(P<0.05)；观察组视力恢复4.3~4.7为31.7%(13/41),低于对照组41.5%(17/41),差异有统计学意义(P<0.05)；两组患者治疗后视网膜静脉循环时间,均低于治疗前,差异有统计学意义(P<0.05)；观察组治疗后视网膜静脉循环时间为8.15±1.30s,低于对照组9.70±1.28s,差异有统计学意义(P<0.05)。结论：丹参注射液离子导入配合蚓激酶治疗早期视网膜静脉阻塞临床疗效较好,提高患者的视力恢复,促进患者康复。
目的：：探討丹參註射液離子導入配閤蚓激酶治療早期視網膜靜脈阻塞患者的臨床效果,併觀察其預後,為臨床提供客觀依據。方法：隨機選擇本院2011-01/2014-04收治的早期RVO患者82例117眼,對照組41例59眼,應用蚓激酶治療；觀察組41例58眼,應用丹參註射液離子導入配閤蚓激酶治療。主要觀察指標為治療效果、觀察患者視力恢複情況及視網膜循環時間等指標。結果：觀察組總有效率為85.4%(35/41),高于對照組68.3%(28/41),差異有統計學意義(P<0.05)；觀察組無效率為14.6%(6/41),低于對照組31.7%(13/41),差異有統計學意義(P<0.05)；觀察組視力恢複4.8~5.0為53.7%(22/41),高于對照組41.5%(17/41),差異有統計學意義(P<0.05)；觀察組視力恢複4.3~4.7為31.7%(13/41),低于對照組41.5%(17/41),差異有統計學意義(P<0.05)；兩組患者治療後視網膜靜脈循環時間,均低于治療前,差異有統計學意義(P<0.05)；觀察組治療後視網膜靜脈循環時間為8.15±1.30s,低于對照組9.70±1.28s,差異有統計學意義(P<0.05)。結論：丹參註射液離子導入配閤蚓激酶治療早期視網膜靜脈阻塞臨床療效較好,提高患者的視力恢複,促進患者康複。
목적：：탐토단삼주사액리자도입배합인격매치료조기시망막정맥조새환자적림상효과,병관찰기예후,위림상제공객관의거。방법：수궤선택본원2011-01/2014-04수치적조기RVO환자82례117안,대조조41례59안,응용인격매치료；관찰조41례58안,응용단삼주사액리자도입배합인격매치료。주요관찰지표위치료효과、관찰환자시력회복정황급시망막순배시간등지표。결과：관찰조총유효솔위85.4%(35/41),고우대조조68.3%(28/41),차이유통계학의의(P<0.05)；관찰조무효솔위14.6%(6/41),저우대조조31.7%(13/41),차이유통계학의의(P<0.05)；관찰조시력회복4.8~5.0위53.7%(22/41),고우대조조41.5%(17/41),차이유통계학의의(P<0.05)；관찰조시력회복4.3~4.7위31.7%(13/41),저우대조조41.5%(17/41),차이유통계학의의(P<0.05)；량조환자치료후시망막정맥순배시간,균저우치료전,차이유통계학의의(P<0.05)；관찰조치료후시망막정맥순배시간위8.15±1.30s,저우대조조9.70±1.28s,차이유통계학의의(P<0.05)。결론：단삼주사액리자도입배합인격매치료조기시망막정맥조새림상료효교호,제고환자적시력회복,촉진환자강복。
Abstract? AlM: To explore the effect of Danshen injection iontophoresis combined with lumbrukinase on early patients with retinal vein occlusion ( RVO ) , and observe the prognosis to provide objective basis for clinical?METHODS: Eighty-two patients ( 117 eyes ) with early RVO were randomly selected in our hospital from January, 2011 to April, 2014, 41 cases (59 eyes) of control group treated with Lumbrokinase. Forty-one cases ( 58 eyes) of the observation group, treated with Danshen injection iontophoresis combined with lumbrokinase. The main indexes were the treatment effect, visual acuity and retinal circulation time.?RESULTS: The total effective rate of the observation group was 85. 4% ( 35/41 ), more than that of control group 68. 3% ( 28/41 ), the difference was statistically significant (P<0. 05). The invalid rate of the observation group was 14. 6% (6/41), lower than that of the control group 31. 7% ( 13/41 ), the difference was statistically significant (P<0. 05). The vision of the observation group 4. 8 ~5. 0 was 53. 7% (22/41), more than that of control group 41. 5% ( 17/41 ), the difference was statistically significant ( P < 0. 05 ). The restore vision of the observation group 4. 3 ~ 4. 7 was 31. 7% (13/41), lower than that of the control group 41. 5% ( 17/41 ), the difference was statistically significant ( P<0. 05 ). After treatment, retinal circulation time of two groups were lower than before treatment, the difference was statistically significant (P<0. 05). After treatment of retinal vein circulation time of the observation group was 8. 15 ± 1. 30s, 9. 70 ± 1. 28s lower than that of the control group, the difference was statistically significant (P<0. 05).?CONCLUSlON: There is better effective on Danshen injection iontophoresis combined with Lumbrokinase for early retinal vein occlusion, and can improve the patient's visual acuity, promote the rehabilitation of patients.
