国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2015年
1期
86-88
,共3页
青光眼%白内障%联合手术%MUC5 AC
青光眼%白內障%聯閤手術%MUC5 AC
청광안%백내장%연합수술%MUC5 AC
?KEYWORDS:glaucoma%cataract%joint surgery%MUC5AC
目的：：探讨青光眼白内障联合手术对青光眼患者泪液黏蛋白5AC水平(MUC5AC)及眼表功能的影响。方法：选择2011-12/2014-06入住我院的28例行青光眼白内障联合手术青光眼患者作为观察组,同时选择28例未行手术治疗的青光眼白内障患者作为对照组,选择同期在我院进行体检的30名健康者作为健康对照组。比较三组受试者术前1 d；术后3,6 mo时的泪液MUC5 AC水平及眼表功能评分。结果：两组患者术前泪液NUC5 AC含量明显低于健康对照组(P<0.05),眼表功能评分明显高于健康对照组(P<0.05)。观察组术后1 mo泪液MUC5 AC水平显著低于术前( P<0.05),术后3 mo MUC5 AC含量逐渐升高至术前水平,术后6 mo时泪液MUC5 AC水平均显著高于术前( P<0.05)；术后1mo眼表功能评分显著高于术前(P<0.05),术后3 mo时,眼表功能评分逐渐降低,术后6 mo时眼表功能评分均显著低于术前(P<0.05)。而对照组在术后6mo期间,随着时间的推移,泪液MUC5 AC含量逐步降低,眼表功能评分逐步升高。结论：青光眼白内障联合手术术后可使青光眼患者MUC5 AC水平暂时性降低,眼表功能评分暂时性升高,但术后3 mo后,可逐步改善。
目的：：探討青光眼白內障聯閤手術對青光眼患者淚液黏蛋白5AC水平(MUC5AC)及眼錶功能的影響。方法：選擇2011-12/2014-06入住我院的28例行青光眼白內障聯閤手術青光眼患者作為觀察組,同時選擇28例未行手術治療的青光眼白內障患者作為對照組,選擇同期在我院進行體檢的30名健康者作為健康對照組。比較三組受試者術前1 d；術後3,6 mo時的淚液MUC5 AC水平及眼錶功能評分。結果：兩組患者術前淚液NUC5 AC含量明顯低于健康對照組(P<0.05),眼錶功能評分明顯高于健康對照組(P<0.05)。觀察組術後1 mo淚液MUC5 AC水平顯著低于術前( P<0.05),術後3 mo MUC5 AC含量逐漸升高至術前水平,術後6 mo時淚液MUC5 AC水平均顯著高于術前( P<0.05)；術後1mo眼錶功能評分顯著高于術前(P<0.05),術後3 mo時,眼錶功能評分逐漸降低,術後6 mo時眼錶功能評分均顯著低于術前(P<0.05)。而對照組在術後6mo期間,隨著時間的推移,淚液MUC5 AC含量逐步降低,眼錶功能評分逐步升高。結論：青光眼白內障聯閤手術術後可使青光眼患者MUC5 AC水平暫時性降低,眼錶功能評分暫時性升高,但術後3 mo後,可逐步改善。
목적：：탐토청광안백내장연합수술대청광안환자루액점단백5AC수평(MUC5AC)급안표공능적영향。방법：선택2011-12/2014-06입주아원적28례행청광안백내장연합수술청광안환자작위관찰조,동시선택28례미행수술치료적청광안백내장환자작위대조조,선택동기재아원진행체검적30명건강자작위건강대조조。비교삼조수시자술전1 d；술후3,6 mo시적루액MUC5 AC수평급안표공능평분。결과：량조환자술전루액NUC5 AC함량명현저우건강대조조(P<0.05),안표공능평분명현고우건강대조조(P<0.05)。관찰조술후1 mo루액MUC5 AC수평현저저우술전( P<0.05),술후3 mo MUC5 AC함량축점승고지술전수평,술후6 mo시루액MUC5 AC수평균현저고우술전( P<0.05)；술후1mo안표공능평분현저고우술전(P<0.05),술후3 mo시,안표공능평분축점강저,술후6 mo시안표공능평분균현저저우술전(P<0.05)。이대조조재술후6mo기간,수착시간적추이,루액MUC5 AC함량축보강저,안표공능평분축보승고。결론：청광안백내장연합수술술후가사청광안환자MUC5 AC수평잠시성강저,안표공능평분잠시성승고,단술후3 mo후,가축보개선。
Abstract?AlM:To investigate the effects of the MUC5AC levels and ocular function of the patients with glaucoma and cataract with combined surgery.? METHODS: Twenty - eight patients treated with glaucoma and cataract combined surgery were chosen as the observation group from December 2011 to June 2014 in our hospital, and other 28 cases of glaucoma and cataract did not undergo surgical treatment were selected as the control group, 30 healthy subjects were as healthy control group. the MUC5AC level and ocular surface score of the three subjects before surgery 1d, after 3 and 6mo were compared.?RESULTS: The NUC5AC of the two groups of patients was significantly lower than that of the healthy control group before surgery (P<0. 05), the ocular function score was significantly higher than the healthy control group ( P<0. 05). After 1mo, the MUC5AC of the observation group were significantly lower than that of before surgery ( P<0. 05), after 3mo MUC5AC content gradually increased to preoperative levels, after 6mo the MUC5AC were significantly higher than before surgery (P<0. 05). After 1mo, ocular function scores were significantly higher than the preoperative ( P< 0. 05 ), while after 3mo, ocular function scores decreased after 6mo of ocular surface function scores were significantly lower than the preoperative (P<0. 05). While the control group after 6mo, with the passage of time, the MUC5AC content gradually reduce, ocular function score increased gradually. ?CONCLUSlON:To treat the patients with glaucoma and cataract with combined surgery, the level of MUC5AC can temporary decrease. Ocular function score can temporary increase in, but after 3mo, it can be gradually improved.
