国际眼科杂志
國際眼科雜誌
국제안과잡지
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY
2015年
1期
55-57
,共3页
血管内皮生长因子%色素上皮生长因子%增殖性糖尿病视网膜病变
血管內皮生長因子%色素上皮生長因子%增殖性糖尿病視網膜病變
혈관내피생장인자%색소상피생장인자%증식성당뇨병시망막병변
? KEYWORDS：vascular endothelial growth factor%pigment epithelium - derived factor%proliferative diabetic retinopathy
增殖性糖尿病视网膜病变( proliferative diabetic retinopathy,PDR)是一种以眼内新生血管形成为特征的糖尿病并发症。眼内新生血管的形成是当今世界主要致盲原因之一。血管内皮生长因子( vascular endothelial growth factor,VEGF)与色素上皮衍生因子( pigment epithelium-derived factor,PEDF)作为眼内新生血管形成最主要的细胞因子,近年来成为研究热点。本文就VEGF和PEDF在PDR中的研究进展进行综述。
增殖性糖尿病視網膜病變( proliferative diabetic retinopathy,PDR)是一種以眼內新生血管形成為特徵的糖尿病併髮癥。眼內新生血管的形成是噹今世界主要緻盲原因之一。血管內皮生長因子( vascular endothelial growth factor,VEGF)與色素上皮衍生因子( pigment epithelium-derived factor,PEDF)作為眼內新生血管形成最主要的細胞因子,近年來成為研究熱點。本文就VEGF和PEDF在PDR中的研究進展進行綜述。
증식성당뇨병시망막병변( proliferative diabetic retinopathy,PDR)시일충이안내신생혈관형성위특정적당뇨병병발증。안내신생혈관적형성시당금세계주요치맹원인지일。혈관내피생장인자( vascular endothelial growth factor,VEGF)여색소상피연생인자( pigment epithelium-derived factor,PEDF)작위안내신생혈관형성최주요적세포인자,근년래성위연구열점。본문취VEGF화PEDF재PDR중적연구진전진행종술。
?Proliferative diabetic retinopathy ( PDR ) is a group of disease characterized by neovascular disease complication of diabetes mellitus. Neovascular diseases of eye are one of the major causes of blindness of the world. Recent studies showed that vascular endothelial growth factor ( VEGF) and pigment epithelium-derived factor ( PEDF ) are now accepted as the key cytokine in the development of diabetic retinopathy. Recent progress in the investigation of VEGF and PEDF of PDR are summarized in this review.
