CAJ | 학술논문

目的：：探索米索前列醇片在促待产妇宫颈成熟与引产的合适用法、用量。方法：选取待产妇168例,随机分成两组,A组待产妇舌下含服100μg米索前列醇片；B组待产妇阴道后穹隆置药50μg。收集两组待产妇用药后的宫颈成熟度、待产时间、产程以及新生儿安全指标等数据,进行统计学分析。结果：舌下含服和阴道给药在促待产妇宫颈成熟、有效率、待产时间、产程等作用上没有明显差别,但舌下含服组待产妇的剖宫产及新生儿窒息比率较低。结论：舌下含服100μg和阴道给药50μg米索前列醇片在有效性上效果相当,但舌下含服组的安全性更高。
목적：：탐색미색전렬순편재촉대산부궁경성숙여인산적합괄용법、용량。방법：선취대산부168례,수궤분성량조,A조대산부설하함복100μg미색전렬순편；B조대산부음도후궁륭치약50μg。수집량조대산부용약후적궁경성숙도、대산시간、산정이급신생인안전지표등수거,진행통계학분석。결과：설하함복화음도급약재촉대산부궁경성숙、유효솔、대산시간、산정등작용상몰유명현차별,단설하함복조대산부적부궁산급신생인질식비솔교저。결론：설하함복100μg화음도급약50μg미색전렬순편재유효성상효과상당,단설하함복조적안전성경고。
Objective:To explore the appropriate use and dosage of misoprostol tablets in parturients with cervical ripening and labor induction. Methods:168 parturients were chosen and divided into two groups randomly. Group A parturients was given 100μg misoprostol tablets by sublingual administration, while 50μg misoprostol was placed in vaginal vault in group B parturients. The data of cervical maturity, expectant time, labor time and neonatal safety of the two groups parturients were collected for statistical analysis. Results:There were no differences in the cervical maturity, effective rate, expectant time and labor time between the two groups partu-rients, but the cesarean section and neonatal asphyxia rates were lower in the Group A parturients. Conclusions:The efficacies of both sublingual and vaginally groups are equivalent, but sublingual group is safer.