CAJ | 학술논문

目的：了解我院2013年金黄色葡萄球菌(Staphylococcus aureus,SAU)的感染现状及耐药性,为临床合理应用抗菌药物提供依据。方法收集分离我院2013年住院及门诊患者送检的SAU菌株共549株,并对其感染现状及耐药性进行分析。结果2013年共分离SAU共549株,占所有分离细菌的比例为8.6%,其中耐甲氧西林金黄色葡萄球菌(Methicil in resistant Staphylococcus aureus,MRSA)326株,在SAU中所占比例为59.4%。药敏结果显示,2013年我院SAU对青霉素的耐药率为96.1%,对万古霉素、替考拉宁及呋喃妥因的敏感性好,而对头孢唑林、氨苄西林-舒巴坦及红霉素等的耐药率均大于30%。326株MRSA菌株来自临床各个标本,如痰液、创面分泌物及脓液等,其中在痰液中检出菌株最多,占52.4%,其次为创面分泌物,占25.5%。临床科室中分离出MRSA最多的科室是重症监护室,占19.9%,其次是骨科、烧伤科和儿科,分别为14.1%、12.9%和12.6%。结论 MRSA的检出率高,临床上需要采取综合措施预防和控制MRSA感染。
목적：료해아원2013년금황색포도구균(Staphylococcus aureus,SAU)적감염현상급내약성,위림상합리응용항균약물제공의거。방법수집분리아원2013년주원급문진환자송검적SAU균주공549주,병대기감염현상급내약성진행분석。결과2013년공분리SAU공549주,점소유분리세균적비례위8.6%,기중내갑양서림금황색포도구균(Methicil in resistant Staphylococcus aureus,MRSA)326주,재SAU중소점비례위59.4%。약민결과현시,2013년아원SAU대청매소적내약솔위96.1%,대만고매소、체고랍저급부남타인적민감성호,이대두포서림、안변서림-서파탄급홍매소등적내약솔균대우30%。326주MRSA균주래자림상각개표본,여담액、창면분비물급농액등,기중재담액중검출균주최다,점52.4%,기차위창면분비물,점25.5%。림상과실중분리출MRSA최다적과실시중증감호실,점19.9%,기차시골과、소상과화인과,분별위14.1%、12.9%화12.6%。결론 MRSA적검출솔고,림상상수요채취종합조시예방화공제MRSA감염。
Objective To investigate the nosocomial infections and drug resistance of Staphylococcus aureus (SAU) in our hospital in 2013,provide the evidence for clinical treatment.Methods Col ected 549 strains of Staphylococcus aureus isolated in 2013 in our hospital,retrospectively analyzed the nosocomial infections and drug resistance.Results In 2013,549 strains of Staphylococcus aureus were isolated, accounting for 8.6%of al strains.There were 326 strains of Methicil in resistant Staphylococcus aureus (MRSAs) included,with the detective rate of 59.4%of Staphylococcus aureus. In vitro susceptibility test, the resistant rate of Staphylococcus aureus to penicil in was 96.1%in 2013. It presented good sensitivity to vancomycin,teicoplanin and nitrofurantoin,but a high drug resistance rate to cefazolin,ampicil in sulbactam,and erythromycin,more than 30%.The separation of Methicil in resistant Staphylococcus aureus came from phlegm,wound secretion,fester,and so on.The highest rate was phlegm,which was 52.4%, and next was wound secretion with the rate of 25.5%.In clinical departments,Methicil in resistant Staphylococcus aureus were isolated most in intensive care unit(ICU),with the proportion of 19.9%,fol owed by the department of orthopedics,department of burn,and paediatrics,and the proportion were 14.1%,12.9%and 12.6%respectively. Conclusion The detection rate of Methicil in resistant Staphylococcus aureus was high in our hospital,comprehensive measures should be taken to prevent and control infection of Methicil in resistant Staphylococcus.