CAJ | 학술논문

目的：观察黛力新与复方利多卡因乳膏联合治疗对带状疱疹后遗神经痛患者的疼痛症状及抑郁情绪的影响。方法将67例确诊为带状疱疹后遗神经痛(PHN)合并抑郁状态的患者随机分为两组,治疗组34例给予黛力新10.5mg,1次/d,同时外用复方利多卡因乳膏,2次/d,连用4w。对照组33例局部外用复方利多卡因乳膏,2次/d,连用4w。于治疗前及治疗后7、14、28d分别采用视觉模拟评分(VAS)评定PHN患者疼痛程度,采用汉密尔顿抑郁评分(HAMD)评价PHN患者抑郁状态的程度。结果治疗组与对照组疼痛评分(VAS)均较治疗前明显下降(<0.01)。治疗组疼痛评分(VAS)和抑郁评分(HAMD)均明显低于对照组(<0.01)。结论黛力新联合复方利多卡因乳膏治疗能够明显改善带状疱疹后遗神经痛患者的躯体疼痛症状和抑郁状态。
목적：관찰대력신여복방리다잡인유고연합치료대대상포진후유신경통환자적동통증상급억욱정서적영향。방법장67례학진위대상포진후유신경통(PHN)합병억욱상태적환자수궤분위량조,치료조34례급여대력신10.5mg,1차/d,동시외용복방리다잡인유고,2차/d,련용4w。대조조33례국부외용복방리다잡인유고,2차/d,련용4w。우치료전급치료후7、14、28d분별채용시각모의평분(VAS)평정PHN환자동통정도,채용한밀이돈억욱평분(HAMD)평개PHN환자억욱상태적정도。결과치료조여대조조동통평분(VAS)균교치료전명현하강(<0.01)。치료조동통평분(VAS)화억욱평분(HAMD)균명현저우대조조(<0.01)。결론대력신연합복방리다잡인유고치료능구명현개선대상포진후유신경통환자적구체동통증상화억욱상태。
Objective To observe the clinical ef ect of Deanxit combined with compound lidocaine cream in treatment of herpes zoster postherpetic neuralgia (PHN) with depression. Methods Sixty-seven patients with PHN combining depression were divided into treatment group and contrast group randomly. The 34 patients in the treatment group were given Deanxit 10.5mg once oral y a day for 4 weeks, and compound lidocaine cream was used external y 2 times a day at the same time. The same dose of compound lidocaine cream was used in the 33 patients of the contrast group. Results VAS scores decreased in two groups ( <0.01).The VAS, and HAMD scores of the treatment group were apparently lower than those of the contrast group ( <0.05). Conclusion Deanxit combined with compound lidocaine cream are ef ective in al eviating ace symptom and depression in PHN.