CAJ | 학술논문

目的：了解和分析住院患者抗真菌药物的使用情况，为临床使用抗真菌药物提供有益的指导和参考。方法对我院2011年2月1日至2011年5月31日住院病例进行回顾性分析，按预先设计的统计表收集抗真菌药物使用病例的临床相关信息，并进行统计分析。结果共分析病例22185份，其中使用抗真菌药物的221例，占0.99％。抗菌药物的应用中，针对性治疗占62.90％，预防性治疗占37.10％。抗真菌药物使用主要为三唑类，以氟康唑(60.18％)和伏立康唑(46.61％)最多，以单种用药为主(85.07％)，联合使用率较低。抗真菌治疗后患者预后良好，76.47％患者治愈和好转。结论我院抗真菌药物的使用以针对性治疗为主，多数为单种用药，氟康唑和伏立康唑是目前最常用的抗真菌药物，治疗后多数患者的预后良好。
목적：료해화분석주원환자항진균약물적사용정황，위림상사용항진균약물제공유익적지도화삼고。방법대아원2011년2월1일지2011년5월31일주원병례진행회고성분석，안예선설계적통계표수집항진균약물사용병례적림상상관신식，병진행통계분석。결과공분석병례22185빈，기중사용항진균약물적221례，점0.99％。항균약물적응용중，침대성치료점62.90％，예방성치료점37.10％。항진균약물사용주요위삼서류，이불강서(60.18％)화복립강서(46.61％)최다，이단충용약위주(85.07％)，연합사용솔교저。항진균치료후환자예후량호，76.47％환자치유화호전。결론아원항진균약물적사용이침대성치료위주，다수위단충용약，불강서화복립강서시목전최상용적항진균약물，치료후다수환자적예후량호。
Objecfive To investigate the usage of antifungal drugs in general hospital, which provide guidance and reference for clinical application of antifungal drugs.Methods A retrospective analysis was carried out in hospi-talized cases of our hospital from February 1st, 2011 to May 31st. Results 22185 cases were retrospectively ana-lyzed. 221 cases of them used antifungal drugs, accounting for about 1%. The usage of antifungal drugs firstly gave to targeted therapy, accounting for 62. 90%. The preventive treatment was 37. 10%. The Fluconazole and voriconazole were used mostly.76.47% of patients were cured and improved.Conclusion The mainly use of antifungal drugs in our hospital was target therapy. Fluconazole and voriconazole was the most used antifungal drugs.