CAJ | 학술논문

围生期心肌病是指在妊娠晚期或分娩后5个月发生的特发性心肌病，临床表现为由于左心室收缩功能障碍引起心力衰竭，该病发生于既往健康的妇女，病因尚不明确。该病的发生率低，死亡率却很高，预后也有很大差异。临床症状主要有呼吸困难、咳嗽、颈静脉扩张、水肿等心力衰竭表现，个别患者可能发生心律失常甚至心肌梗死。诊断主要依靠超声心动图、心脏磁共振检查等。对该病可应用强心、利尿及抗凝药物治疗。有些患者的临床症状和超声心动图表现为迅速改善并恢复正常；而有些患者临床症状迅速恶化，药物治疗根本无效，由持续性左心室功能障碍发展为慢性心力衰竭，可以考虑使用机械性心室辅助装置及心脏移植等方法。综述该病在病因研究、诊断、治疗及预后方面的进展情况。
위생기심기병시지재임신만기혹분면후5개월발생적특발성심기병，림상표현위유우좌심실수축공능장애인기심력쇠갈，해병발생우기왕건강적부녀，병인상불명학。해병적발생솔저，사망솔각흔고，예후야유흔대차이。림상증상주요유호흡곤난、해수、경정맥확장、수종등심력쇠갈표현，개별환자가능발생심률실상심지심기경사。진단주요의고초성심동도、심장자공진검사등。대해병가응용강심、이뇨급항응약물치료。유사환자적림상증상화초성심동도표현위신속개선병회복정상；이유사환자림상증상신속악화，약물치료근본무효，유지속성좌심실공능장애발전위만성심력쇠갈，가이고필사용궤계성심실보조장치급심장이식등방법。종술해병재병인연구、진단、치료급예후방면적진전정황。
Peripartum cardiomyopathy is defined as an idiopathic cardiomyopathy manifested as heart failure due to left ventricular systolic dysfunction toward the end of pregnancy or in five months after delivery when no other causes of heart failure ars found. Peripartum cardiomyopathy occurs in previously healthy woman,with unknown origin. Although the incidence is low, the mortality rate is high,and the prognosis is different. The patients commonly have dyspnea,cough,neck vein distension and edema,some patients even occurred arrhythmia and myocardial infarction. Diagnosis relies mainly on echocardiography and magnetic resonance images. The disease can be treated by positive myodynamia ,diuresis,and anticoagulant drugs. In some patients the clinical symptoms and ultrasonic cardiogram quickly improve and return normal;but in other patients,the clinical symptoms rapidly deteriorating and the drug treatment is ineffective ,if persistent left ventricular dysfunction develop to chronic heart failure,ventricular assist devices and cardiac transplantation maybe required. Summarize the etiology ,diagnosis and treatment management of the disease.