中国药物应用与监测
中國藥物應用與鑑測
중국약물응용여감측
CHINESE JOURNAL OF DRUG APPLICATION AND MONITORING
2014年
6期
380-382,383
,共4页
抗菌药物%高龄患者%用药频度%药物利用指数%处方分析
抗菌藥物%高齡患者%用藥頻度%藥物利用指數%處方分析
항균약물%고령환자%용약빈도%약물이용지수%처방분석
Antibacterials%Elderly patients%DDDs%DUI%Prescription analysis
目的：通过评价抗菌药物用药现状，为高龄患者合理用药提供参考。方法：采用回顾性分析方法，收集2013年1–12月门诊高龄患者抗菌药物处方，共计1514张，利用用药频度（DDDs）和药物利用指数（DUI）分析法，对用药情况进行统计分析。结果：我中心使用的20种抗菌药物的DUI在0.32~1.42之间；DDDs排名前3位分别是头孢菌素类、喹诺酮类和大环内酯类，药品品种依次是头孢呋辛酯、左氧氟沙星（口服制剂）和头孢呋辛钠（注射制剂）。女性患者抗菌药物使用量所占比例（64.07％）高于男性，患者年龄主要分布在91~95岁之间。结论：我中心高龄患者门诊抗菌药物应用基本合理，但仍存在抗菌药物注射剂型使用比例偏高、用药剂量偏大等情况，应加强临床监管。
目的：通過評價抗菌藥物用藥現狀，為高齡患者閤理用藥提供參攷。方法：採用迴顧性分析方法，收集2013年1–12月門診高齡患者抗菌藥物處方，共計1514張，利用用藥頻度（DDDs）和藥物利用指數（DUI）分析法，對用藥情況進行統計分析。結果：我中心使用的20種抗菌藥物的DUI在0.32~1.42之間；DDDs排名前3位分彆是頭孢菌素類、喹諾酮類和大環內酯類，藥品品種依次是頭孢呋辛酯、左氧氟沙星（口服製劑）和頭孢呋辛鈉（註射製劑）。女性患者抗菌藥物使用量所佔比例（64.07％）高于男性，患者年齡主要分佈在91~95歲之間。結論：我中心高齡患者門診抗菌藥物應用基本閤理，但仍存在抗菌藥物註射劑型使用比例偏高、用藥劑量偏大等情況，應加彊臨床鑑管。
목적：통과평개항균약물용약현상，위고령환자합리용약제공삼고。방법：채용회고성분석방법，수집2013년1–12월문진고령환자항균약물처방，공계1514장，이용용약빈도（DDDs）화약물이용지수（DUI）분석법，대용약정황진행통계분석。결과：아중심사용적20충항균약물적DUI재0.32~1.42지간；DDDs배명전3위분별시두포균소류、규낙동류화대배내지류，약품품충의차시두포부신지、좌양불사성（구복제제）화두포부신납（주사제제）。녀성환자항균약물사용량소점비례（64.07％）고우남성，환자년령주요분포재91~95세지간。결론：아중심고령환자문진항균약물응용기본합리，단잉존재항균약물주사제형사용비례편고、용약제량편대등정황，응가강림상감관。
[ABSTRACT]Objective:To provide the evidence on rational use of drugs for elderly patients by evaluating the utilization of antibacterial agents.Methods:A total of 1514 antibacterial outpatient prescriptions of elderly patients were collected from January to December in 2013 of our center. The varieties of antibacterials were analyzed by DDDs and drug utilization index (DUI). Results: The DUI of 20 kinds of antibacterials used in outpatient were in the range of 0.32 – 1.42. The top 3 antibacterials in terms of DDDs were cephalosporins, quinolones and macrolides, and the drugs were cefuroxime axetil, levolfoxacin (oral preparation) and cefuroxime sodium(injection preparation). The usage proportion in female patients was higher than that of male patients, accounting for 64.07%, the age of the patients was mainly 91 – 95 years.Conclusion:The application of antibacterials was basically rational for elderly patients in our center, but the irrational uses of drugs were observed such as high constituent ratio and the high dosage use of antibacterials injection, which should be supervised in clinic.
