国外医学(医学地理分册)
國外醫學(醫學地理分冊)
국외의학(의학지리분책)
FOREIGN MEDICAL SCIENCES(SECTION OF MEDGEOGRAPHY)
2014年
4期
279-282
,共4页
吸烟%甲状腺功能亢进%甲状腺功能减退%非毒性甲状腺肿%分化型甲状腺癌
吸煙%甲狀腺功能亢進%甲狀腺功能減退%非毒性甲狀腺腫%分化型甲狀腺癌
흡연%갑상선공능항진%갑상선공능감퇴%비독성갑상선종%분화형갑상선암
smoking%hyperthyroidism%hypothyroidism%nontoxic goiter%differentiated thyroid carcinoma
大规模人口调查统计显示,吸烟能够降低血清TSH ,升高FT3、FT4水平,这一作用与是否存在缺碘有直接的相关性,现有资料表明碘充足地区存在这一效应,即吸烟提高了甲状腺功能亢进症的发病率。而在碘缺乏地区,吸烟者非毒性甲状腺肿大的发病率更高且甲状腺体积更大。吸烟者不易患甲状腺癌,尤其是乳头状甲状腺癌,这跟吸烟的年限及吸烟量有关,但这一观点尚需更多的证据支持,且其相关机制尚不清楚。
大規模人口調查統計顯示,吸煙能夠降低血清TSH ,升高FT3、FT4水平,這一作用與是否存在缺碘有直接的相關性,現有資料錶明碘充足地區存在這一效應,即吸煙提高瞭甲狀腺功能亢進癥的髮病率。而在碘缺乏地區,吸煙者非毒性甲狀腺腫大的髮病率更高且甲狀腺體積更大。吸煙者不易患甲狀腺癌,尤其是乳頭狀甲狀腺癌,這跟吸煙的年限及吸煙量有關,但這一觀點尚需更多的證據支持,且其相關機製尚不清楚。
대규모인구조사통계현시,흡연능구강저혈청TSH ,승고FT3、FT4수평,저일작용여시부존재결전유직접적상관성,현유자료표명전충족지구존재저일효응,즉흡연제고료갑상선공능항진증적발병솔。이재전결핍지구,흡연자비독성갑상선종대적발병솔경고차갑상선체적경대。흡연자불역환갑상선암,우기시유두상갑상선암,저근흡연적년한급흡연량유관,단저일관점상수경다적증거지지,차기상관궤제상불청초。
Investigations of large‐scale population have indicated that smoking is likely to decrease serum TSH , meanwhile increase serum FT3 and FT4 levels .However ,this effect correlates with iodine levels .Data available have showed this effect occurred in iodine‐sufficient areas ,which further leads to the development of hyperthyroid‐ism .In iodine‐insufficient areas ,higher nontoxic goiter incidence and lager thyroid volume are found in smokers , who are less likely to suffer from thyroid cancer , especially papillary thyroid carcinoma . This phenomenon is thought to be related to the dosage of smoking ,but the mechanism remains unclear ,which needs further investiga‐tion .