CAJ | 학술논문

目的：分析急性泛发性发疹性脓疱病（AGEP）的病因、临床特点、诊断，探讨其治疗。方法回顾性分析2004年1月—2011年11月我院收治的14例AGEP患者的诊断和治疗经过。结果14例患者中13例有用药史，4例有上呼吸道感染史，有发热，白细胞增高。病程6～18 d。糖皮质激素或糖皮质激素联合丙种球蛋白治疗AGEP疗效确切。结论药物、感染是AGEP的主要诱因。中成药中改善循环的药物（针剂）成为我院就诊患者AGEP的主要诱因，其次是抗生素。一旦诱因去除，皮损可能在15 d之内消退，且没有明显不良反应。
목적：분석급성범발성발진성농포병（AGEP）적병인、림상특점、진단，탐토기치료。방법회고성분석2004년1월—2011년11월아원수치적14례AGEP환자적진단화치료경과。결과14례환자중13례유용약사，4례유상호흡도감염사，유발열，백세포증고。병정6～18 d。당피질격소혹당피질격소연합병충구단백치료AGEP료효학절。결론약물、감염시AGEP적주요유인。중성약중개선순배적약물（침제）성위아원취진환자AGEP적주요유인，기차시항생소。일단유인거제，피손가능재15 d지내소퇴，차몰유명현불량반응。
ObjectiveTo explore the causes, diagnosis and treatment of acute generalized exanthematous pustulosis (AGEP). MethodsFourteen AGEP patients admitted to our hospital from January 2004 to November 2011 were retrospectively analyzed. ResultsThirteen of the 14 AGEP patients had a history of drug-intake, and four patients had a history of upper respiratory tract infection. The main manifestations were fever and sudden onset eruptions characterized by generalized erythema and non-follicular pustules.ConclusionsFor AGEP, the most common cause was drug-intake, especially traditional Chinese medicine injections with activating blood circulation and resolving stasis functions, second by the antibiotics. Fever and leukocytosis are universal. Once the inciting agent is discontinued or cleared, the eruption resolves within 15 days without sequelae.