中国中西医结合肾病杂志
中國中西醫結閤腎病雜誌
중국중서의결합신병잡지
CHINESE JOURNAL OF INTEGRATED TRADITIONAL AND WESTERN NEPHROLOGY
2014年
12期
1072-1076
,共5页
刘玉梅%鲍宏达%黄亚娟%汪年松
劉玉梅%鮑宏達%黃亞娟%汪年鬆
류옥매%포굉체%황아연%왕년송
贫血%慢性肾脏病%妊娠结局%肾穿刺%肾脏替代治疗
貧血%慢性腎髒病%妊娠結跼%腎穿刺%腎髒替代治療
빈혈%만성신장병%임신결국%신천자%신장체대치료
Anemia%Chronic kidney disease%Pregnancy outcome%Renal biopsy%Renal replacement therapy
目的:了解起病与妊娠相关的肾脏病女性患者的发病率、病因及一般情况。方法:收集2004年8月~2013年1月肾脏科,于妊娠期间及产后6个月内诊断为肾脏病的女性患者,并记录其临床资料。结果:起病与妊娠相关的肾脏病女性的发病率为1.49%(43/2891),53.4%为CKD1~2期患者,6名女性进入终末期肾脏病(0.208%)。67.4%在妊娠期间诊断为肾脏病,大部分因蛋白尿发现(46.5%)。最多的临床诊断为慢性肾小球肾炎(27.9%),最多的病理诊断为IgA肾病(50%)。平均血红蛋白浓度为(105±30)g/L,血钙磷代谢异常比例为20.9%。妊娠至诊断肾脏病的平均时间为(128±288)周(中位数25周),她们的剖宫产比例及死产比例均高于健康妊娠女性(53.8%比16.7%,60%比0%,P<0.05)。43名中的8名女性接受肾脏替代治疗。结论:起病与妊娠相关的肾脏病女性患者的发病率高于文献报道,这些女性的临床及病理诊断与我国慢性肾脏病的流行病学一致,他们贫血及钙磷代谢的控制情况不理想。
目的:瞭解起病與妊娠相關的腎髒病女性患者的髮病率、病因及一般情況。方法:收集2004年8月~2013年1月腎髒科,于妊娠期間及產後6箇月內診斷為腎髒病的女性患者,併記錄其臨床資料。結果:起病與妊娠相關的腎髒病女性的髮病率為1.49%(43/2891),53.4%為CKD1~2期患者,6名女性進入終末期腎髒病(0.208%)。67.4%在妊娠期間診斷為腎髒病,大部分因蛋白尿髮現(46.5%)。最多的臨床診斷為慢性腎小毬腎炎(27.9%),最多的病理診斷為IgA腎病(50%)。平均血紅蛋白濃度為(105±30)g/L,血鈣燐代謝異常比例為20.9%。妊娠至診斷腎髒病的平均時間為(128±288)週(中位數25週),她們的剖宮產比例及死產比例均高于健康妊娠女性(53.8%比16.7%,60%比0%,P<0.05)。43名中的8名女性接受腎髒替代治療。結論:起病與妊娠相關的腎髒病女性患者的髮病率高于文獻報道,這些女性的臨床及病理診斷與我國慢性腎髒病的流行病學一緻,他們貧血及鈣燐代謝的控製情況不理想。
목적:료해기병여임신상관적신장병녀성환자적발병솔、병인급일반정황。방법:수집2004년8월~2013년1월신장과,우임신기간급산후6개월내진단위신장병적녀성환자,병기록기림상자료。결과:기병여임신상관적신장병녀성적발병솔위1.49%(43/2891),53.4%위CKD1~2기환자,6명녀성진입종말기신장병(0.208%)。67.4%재임신기간진단위신장병,대부분인단백뇨발현(46.5%)。최다적림상진단위만성신소구신염(27.9%),최다적병리진단위IgA신병(50%)。평균혈홍단백농도위(105±30)g/L,혈개린대사이상비례위20.9%。임신지진단신장병적평균시간위(128±288)주(중위수25주),저문적부궁산비례급사산비례균고우건강임신녀성(53.8%비16.7%,60%비0%,P<0.05)。43명중적8명녀성접수신장체대치료。결론:기병여임신상관적신장병녀성환자적발병솔고우문헌보도,저사녀성적림상급병리진단여아국만성신장병적류행병학일치,타문빈혈급개린대사적공제정황불이상。
Objective:To learn the incidence,causes and general condition of women whose kidney disease onset related to pregnancy. Methods:Women of Han ethnics whose kidney disease onset related to pregnancy were collected from August 2004 to Jan-uary 2013 in nephrology department Inclusive criteria was women diagnosed with kidney disease during pregnancy or within six -month after delivery. Clinical data were recorded. Results:The incidence of women whose kidney disease onset related to pregnancy is 1. 49%(43/2 891). 53. 4% women in chronic kidney disease stage 1 ~2. Six women proceeded to end stage renal disease (0. 208%). Most were discovered during pregnancy(67. 4%),for discovering proteinuria(46. 5%). The most clinical diagnosis was chronic glomerularnephritis(27. 9%). The most pathological diagnosis was IgA nephropathy(50%). Mean hemoglobin was (105 ± 30)g/L. Percentage of calcium and phosphorus abnormalities was 20. 9%. Average week from gravidity till kidney disease di-agnosis was(128 ± 288)weeks,median for 25 weeks. Their proportion of cesarean section and stillbirth were higher than normal pregnant women(53. 8% VS 16. 7% and 60% VS 0%,P<0. 05). Eight out of 43 women received renal replacement therapy. Conclusion:The incidence of women whose kidney disease onset related to pregnancy is higher than reported. The clinical and patho-logical diagnosis of these women are consistent with epidemiology of kidney disease in China. Management of their anemia and calcium or phosphorus were not optimistic.