世界中医药
世界中醫藥
세계중의약
WORLD CHINESE MEDICINE
2014年
12期
1644-1646
,共3页
李玉棠%萨仁图雅%乌云格日勒%王月红%阿日嘎太%水灵%乌力吉木仁%斯楞格%萨其拉
李玉棠%薩仁圖雅%烏雲格日勒%王月紅%阿日嘎太%水靈%烏力吉木仁%斯楞格%薩其拉
리옥당%살인도아%오운격일륵%왕월홍%아일알태%수령%오력길목인%사릉격%살기랍
蒙医温针疗法%大脑中动脉阻塞再灌注%神经功能%血管内皮生长因子%脑水肿
矇醫溫針療法%大腦中動脈阻塞再灌註%神經功能%血管內皮生長因子%腦水腫
몽의온침요법%대뇌중동맥조새재관주%신경공능%혈관내피생장인자%뇌수종
Mongolian Warm Acupuncture Therapy%Middle cerebral Artery Occlusion and Reperfusion%Nerve Function%Vascular Endothelial Growth Factor
目的：探讨蒙医温针对大鼠局灶性脑缺血再灌注后脑组织 VEGF 水平、脑梗死体积，脑含水量的影响。方法：将雄性 SD大鼠随机分为蒙医温针组、针刺组、尼莫地平组、假手术组、模型组5组。采用改良线栓法建立大鼠中动脉阻塞再灌注模型，各组在造模成功1 h 时进行治疗，1次／d，假手术组和模型组不给于治疗。各组大鼠在术后24 h 进行神经功能评分及测脑组织VEGF 水平和脑梗死体积及脑含水量。结果：假手术组无神经功能缺损症状，蒙医温针组与各组比较脑组织 VEGF 含量有统计学意义，各组脑梗死体积、脑含水量与假手术组比较均有统计学意义，蒙医温针组脑梗死体积、脑含水量与模型组比较有统计学意义。结论：蒙医温针有改善大鼠局灶性脑梗死后的神经功能和减轻脑水肿、降低脑梗死体积作用。蒙医温针治疗缺血性脑卒中进行早期干预具有十分重要的临床意义。
目的：探討矇醫溫針對大鼠跼竈性腦缺血再灌註後腦組織 VEGF 水平、腦梗死體積，腦含水量的影響。方法：將雄性 SD大鼠隨機分為矇醫溫針組、針刺組、尼莫地平組、假手術組、模型組5組。採用改良線栓法建立大鼠中動脈阻塞再灌註模型，各組在造模成功1 h 時進行治療，1次／d，假手術組和模型組不給于治療。各組大鼠在術後24 h 進行神經功能評分及測腦組織VEGF 水平和腦梗死體積及腦含水量。結果：假手術組無神經功能缺損癥狀，矇醫溫針組與各組比較腦組織 VEGF 含量有統計學意義，各組腦梗死體積、腦含水量與假手術組比較均有統計學意義，矇醫溫針組腦梗死體積、腦含水量與模型組比較有統計學意義。結論：矇醫溫針有改善大鼠跼竈性腦梗死後的神經功能和減輕腦水腫、降低腦梗死體積作用。矇醫溫針治療缺血性腦卒中進行早期榦預具有十分重要的臨床意義。
목적：탐토몽의온침대대서국조성뇌결혈재관주후뇌조직 VEGF 수평、뇌경사체적，뇌함수량적영향。방법：장웅성 SD대서수궤분위몽의온침조、침자조、니막지평조、가수술조、모형조5조。채용개량선전법건립대서중동맥조새재관주모형，각조재조모성공1 h 시진행치료，1차／d，가수술조화모형조불급우치료。각조대서재술후24 h 진행신경공능평분급측뇌조직VEGF 수평화뇌경사체적급뇌함수량。결과：가수술조무신경공능결손증상，몽의온침조여각조비교뇌조직 VEGF 함량유통계학의의，각조뇌경사체적、뇌함수량여가수술조비교균유통계학의의，몽의온침조뇌경사체적、뇌함수량여모형조비교유통계학의의。결론：몽의온침유개선대서국조성뇌경사후적신경공능화감경뇌수종、강저뇌경사체적작용。몽의온침치료결혈성뇌졸중진행조기간예구유십분중요적림상의의。
Objective:To explore the effect of the Mongolian warm acupuncture on VEGF levels in brain tissue,infarct volume,brain water content in rats with cerebral ischemia after reperfusion.Methods:Male SD rats were randomly divided into Mongolian warm acu-puncture group,acupuncture group,nimodipine group,sham operation group,and model group.Modified suture method was used to set up artery occlusion in rats occlusion and reperfusion model.Rats in each group except sham group and model group were treated for one hour once a day after being successfully modelled.The nerve function,VEGF levels in brain tissue,infarct volume and brain water con-tent after 24 hours of surgery were measured.Results:The sham operation group had no nerve functional defect symptoms,and Mongoli-an warm acupuncture group showed significantly different outcomes in VEGF levels in the brain tissue compared with other groups;in-farct volume and brain water content in each group were significantly different from those of the sham operation group,and Mongolian warm acupuncture group had significant differences in terms of infarct volume and brain water content compared with the model group. Conclusion:Mongolian warm acupuncture can improve rat neurological function after focal cerebral infarction and ease cerebral edema and reduce infarct volume effect.Mongolian warm acupuncture has very important clinical significance to treat ischemic stroke early in-tervention.
