CAJ | 학술논문

为明确多菌灵质量浓度与蚯蚓体内乙酰胆碱酯酶（AChE）、谷胱甘肽S-转移酶（GSTs）和羧酸酯酶（CarE）3种解毒酶活性之间的剂量效应关系，为多菌灵的安全使用及对相关动物的毒害研究提供参考，利用赤峰周边地区蔬菜大棚的蚯蚓，进行多菌灵0．75 g／L、1．00 g／L、1．25 g／L、1．50 g／L、1．75 g／L 和2．00 g／L 6个质量浓度对蚯蚓体内3种解毒酶活性的影响试验。结果表明：与对照组（蒸馏水）相比，多菌灵对蚯蚓体内的乙酰胆碱酯酶整体起抑制作用，在多菌灵浓度为1．75 g／L 时酶活性最低，为105．625μmol／L；对谷胱甘肽 S-转移酶整体起诱导促进作用，在多菌灵浓度为1．00 g／L 时酶活性最高，为17．343μmol／L；对羧酸酯酶活性，在多菌灵浓度小于1．25 g／L 时表现为诱导促进作用，大于1．25 g／L 时表现为抑制作用。
위명학다균령질량농도여구인체내을선담감지매（AChE）、곡광감태S-전이매（GSTs）화최산지매（CarE）3충해독매활성지간적제량효응관계，위다균령적안전사용급대상관동물적독해연구제공삼고，이용적봉주변지구소채대붕적구인，진행다균령0．75 g／L、1．00 g／L、1．25 g／L、1．50 g／L、1．75 g／L 화2．00 g／L 6개질량농도대구인체내3충해독매활성적영향시험。결과표명：여대조조（증류수）상비，다균령대구인체내적을선담감지매정체기억제작용，재다균령농도위1．75 g／L 시매활성최저，위105．625μmol／L；대곡광감태 S-전이매정체기유도촉진작용，재다균령농도위1．00 g／L 시매활성최고，위17．343μmol／L；대최산지매활성，재다균령농도소우1．25 g／L 시표현위유도촉진작용，대우1．25 g／L 시표현위억제작용。
The healthy earthworms from vegetable greenhouses in Chifeng City were treated with carbendazim with six mass concentrations (0.75 g/L,1.00 g/L,1.25 g/L,1.50 g/L,1.75 g/L and 2.00 g/L)to study the dose-effect relationship between carbendazim concentration and activity of AChE,GSTs and CarE and to provide a reference for safe use and poison research of carbendazim.Carbendazim has the inhibition effect on AChE activity overall and the AChE activity is 105.625 mol/L (minimum)when carbendazim concentration is 1.75 g/L.Carbendazim has the promotion effect on GSTs activity overall and the GSTs activity is up to 17.343 mol/L (maximum)when carbendazim concentration is 1.00 g/L.The CarE activity is induced and promoted when carbendazim concentration is less than 1.25 g/L,and the CarE activity is inhibited when carbendazim concentration is higher than 1.25 g/L.