实用临床医药杂志
實用臨床醫藥雜誌
실용림상의약잡지
JOURNAL OF JIANGSU CLINICAL MEDICINE
2014年
22期
38-40
,共3页
非小细胞肺癌%吉非替尼%皮疹%腹泻
非小細胞肺癌%吉非替尼%皮疹%腹瀉
비소세포폐암%길비체니%피진%복사
non-small cell lung cancer%gefitnib%skin rash%diarrhea
目的:观察吉非替尼治疗晚期非小细胞肺癌(NSCLC)的临床疗效及不良反应,并探讨相关护理方案。方法选取晚期 NSCLC 患者110例,给予吉非替尼250 mg /d 治疗。评价近期疗效,观察不良反应并总结相关护理工作。结果客观缓解率为14.5%,疾病控制率为59.1%。主要不良反应为皮疹54例,腹泻32例,恶心呕吐14例,转氨酶升高13例,无患者因不耐受而停药。结论吉非替尼能够一定程度缓解 NSCLC 进展,用药期间要针对不良反应加强护理。
目的:觀察吉非替尼治療晚期非小細胞肺癌(NSCLC)的臨床療效及不良反應,併探討相關護理方案。方法選取晚期 NSCLC 患者110例,給予吉非替尼250 mg /d 治療。評價近期療效,觀察不良反應併總結相關護理工作。結果客觀緩解率為14.5%,疾病控製率為59.1%。主要不良反應為皮疹54例,腹瀉32例,噁心嘔吐14例,轉氨酶升高13例,無患者因不耐受而停藥。結論吉非替尼能夠一定程度緩解 NSCLC 進展,用藥期間要針對不良反應加彊護理。
목적:관찰길비체니치료만기비소세포폐암(NSCLC)적림상료효급불량반응,병탐토상관호리방안。방법선취만기 NSCLC 환자110례,급여길비체니250 mg /d 치료。평개근기료효,관찰불량반응병총결상관호리공작。결과객관완해솔위14.5%,질병공제솔위59.1%。주요불량반응위피진54례,복사32례,악심구토14례,전안매승고13례,무환자인불내수이정약。결론길비체니능구일정정도완해 NSCLC 진전,용약기간요침대불량반응가강호리。
ABSTRACT:Objective To observe the clinical effects of and side reaction to gefitnib in treat-ment of non-small cell lung cancer (NSCLC),and to discuss related nursing interventions.Meth-ods A total of 110 NSCLC patients were administrated with gefitinib 250 mg per day.Response rate and side effects were observed regularly,and nursing experience was summarized after treat-ment.Results Overall response rate and disease control rate was 14.5% and 59%,respectively. Out of 110 patients,54 with skin rash,32 with diarrhea,14 with nausea and 13 with increased aminotransferase,but were reversible by nursing care.Conclusion Gefitnib shows effects in treat-ing NSCLC,and intensive nursing care is required to prevent side reactions.