CAJ | 학술논문

为观察达标心率对缺血型心肌病（ICM ）和扩张型心肌病（DCM ）患者预后的影响，所有入选ICM 和DCM 患者均给予常规抗心力衰竭药物及β受体阻滞剂（β‐b）治疗，使心率维持于55次／分～60次／分，观察随访1年时的病死率、再入院率、舒张末期左室内径（LVEDd）、左室射血分数（LVEF）、氨基末端脑利钠肽前体（NT‐proBNP）水平来评估二者的预后。结果显示，随访结束时ICM患者较DCM患者再入院率低（P＝0．037），LVEDd低（P＝0．034），LVEF高（P＝0．028），收缩压高（P＝0．029）；对于ICM患者，随访结束时较出院时LVEDd低（P＝0．047），LVEF高（P＝0．018），收缩压高（P＝0．042）。因此，心率达标对ICM患者有助于改善预后，对DCM患者改善不明显，ICM患者心率达标时获益更大。
위관찰체표심솔대결혈형심기병（ICM ）화확장형심기병（DCM ）환자예후적영향，소유입선ICM 화DCM 환자균급여상규항심력쇠갈약물급β수체조체제（β‐b）치료，사심솔유지우55차／분～60차／분，관찰수방1년시적병사솔、재입원솔、서장말기좌실내경（LVEDd）、좌실사혈분수（LVEF）、안기말단뇌리납태전체（NT‐proBNP）수평래평고이자적예후。결과현시，수방결속시ICM환자교DCM환자재입원솔저（P＝0．037），LVEDd저（P＝0．034），LVEF고（P＝0．028），수축압고（P＝0．029）；대우ICM환자，수방결속시교출원시LVEDd저（P＝0．047），LVEF고（P＝0．018），수축압고（P＝0．042）。인차，심솔체표대ICM환자유조우개선예후，대DCM환자개선불명현，ICM환자심솔체표시획익경대。
In order to observe the influence of standard heart rate on prognosis in patients with ICM and DCM, all the ICM and DCM patients were given regular anti‐HF drugs and β‐blocher, keeping the heart rate at 55 bpm ~ 60 bpm. By observing the mortality rate, readmission rate, left ventricular end‐diastolic dimension(LVEDd), left ventricular ejection fraction(LVEF), N‐terminal proBNP (NT‐proBNP) after one year to evaluate their prognosis. The outcomes were that, at the end of follow‐up, the ICM patients had lower readmission rate (P=0. 037), lower LVEDd (P=0. 034), higher LVEF (P=0. 028) and higher systolic pressure (P=0. 029) than DCM patients. As to the ICM patients at the end of follow‐up, it had lower LVEDd (P=0. 047), higher LVEF (P=0. 018) and higher systolic pressure (P=0. 042) than discharged. So, as to ICM patients, standard heart rate was benefit to improving the prognosis, but it was not significant about DCM patients. The ICM patients had more profits than DCM patients.