CAJ | 학술논문

目的：分析2型糖尿病采用七味白术散加减辅助治疗的临床疗效和安全性。方法：采用随机数字表法将167例2型糖尿病患者分为两组，对照组予磺脲类、双胍类等降糖药或者联合胰岛素治疗，观察组在对照组基础上予七味白术散加减治疗，对比60d后空腹血糖、餐后血糖、糖化血红蛋白指标和药物安全性。结果：两组均能够降低治疗后生化指标，但观察组降低治疗后生化指标幅度明显高于对照组，P<0.05；观察组总有效率为96.43%，明显高于对照组87.95%，P<0.05；观察组不良反应发生率为2.38%，明显低于对照组10.84%，P<0.05。结论：七味白术散辅助治疗2型糖尿病疗效确切，能够通过多途径、多靶点发挥降血糖作用，而且可保护胰腺功能，不良反应少，建议临床继续探讨和推广。
목적：분석2형당뇨병채용칠미백술산가감보조치료적림상료효화안전성。방법：채용수궤수자표법장167례2형당뇨병환자분위량조，대조조여광뇨류、쌍고류등강당약혹자연합이도소치료，관찰조재대조조기출상여칠미백술산가감치료，대비60d후공복혈당、찬후혈당、당화혈홍단백지표화약물안전성。결과：량조균능구강저치료후생화지표，단관찰조강저치료후생화지표폭도명현고우대조조，P<0.05；관찰조총유효솔위96.43%，명현고우대조조87.95%，P<0.05；관찰조불량반응발생솔위2.38%，명현저우대조조10.84%，P<0.05。결론：칠미백술산보조치료2형당뇨병료효학절，능구통과다도경、다파점발휘강혈당작용，이차가보호이선공능，불량반응소，건의림상계속탐토화추엄。
Objective: To analyze clinical efficacy and safety of Qiwei Baizhu San on diabetes II. Methods: 167 patients with diabetes II were randomly divided into the control group and the observation group. The control group was given sulfonylureas, biguanides, or plus insulin; another was given Qiwei Baizhu San more. FPG in 60d, PBG, glycated hemoglobin index and safety of drugs were compared. Results:The two groups could decrease biochemical indexes after treatment, but the observation group was better (P<0.05);the total efficacy in the observation was 96.43%, obviously higher than 87.95%in the control (P<0.05); the rate of adverse reactions in the observation was 2.38%, obviously lower than 10.84%in the control (P<0.05). Conclusion:Qiwei Baizhu San showed good clinical efficacy, could reduce blood sugar through multi-paths and multi-targets, protect pancreatic function, with less adverse reactions, and was worthy of promotion.