中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
31期
52-53,54
,共3页
四物蠲痹汤%强直性脊柱炎%中药%疗效%安全性
四物蠲痺湯%彊直性脊柱炎%中藥%療效%安全性
사물견비탕%강직성척주염%중약%료효%안전성
The Siwu Juanbi decoction%Ankylosing spondylitis%TCM medicine%Efficacy%Safety
目的：评价四物蠲痹汤加减治疗瘀血阻滞型强直性脊柱炎（AS）的疗效和安全性。方法：将确诊的60例AS患者，随机分为治疗组和对照组，各30例，分别予四物蠲痹汤和双氯芬酸、甲氨喋呤、柳氮磺胺吡啶片等联合药物。3个疗程后，观察临床指标、实验室检查和安全性指标。结果：两组总有效率分别为93.3%和80.0%（P<0.05）；患者的临床指标以及实验室检查均有所改善，其中治疗组较对照组更为明显（均P<0.05）；两组间的安全性有明显差异（P<0.05）。结论：四物蠲痹汤能有效地缓解AS患者的临床症状，控制病情的急性发展，安全性较高，是治疗AS活动期的一个值得应用的药物。
目的：評價四物蠲痺湯加減治療瘀血阻滯型彊直性脊柱炎（AS）的療效和安全性。方法：將確診的60例AS患者，隨機分為治療組和對照組，各30例，分彆予四物蠲痺湯和雙氯芬痠、甲氨喋呤、柳氮磺胺吡啶片等聯閤藥物。3箇療程後，觀察臨床指標、實驗室檢查和安全性指標。結果：兩組總有效率分彆為93.3%和80.0%（P<0.05）；患者的臨床指標以及實驗室檢查均有所改善，其中治療組較對照組更為明顯（均P<0.05）；兩組間的安全性有明顯差異（P<0.05）。結論：四物蠲痺湯能有效地緩解AS患者的臨床癥狀，控製病情的急性髮展，安全性較高，是治療AS活動期的一箇值得應用的藥物。
목적：평개사물견비탕가감치료어혈조체형강직성척주염（AS）적료효화안전성。방법：장학진적60례AS환자，수궤분위치료조화대조조，각30례，분별여사물견비탕화쌍록분산、갑안첩령、류담광알필정편등연합약물。3개료정후，관찰림상지표、실험실검사화안전성지표。결과：량조총유효솔분별위93.3%화80.0%（P<0.05）；환자적림상지표이급실험실검사균유소개선，기중치료조교대조조경위명현（균P<0.05）；량조간적안전성유명현차이（P<0.05）。결론：사물견비탕능유효지완해AS환자적림상증상，공제병정적급성발전，안전성교고，시치료AS활동기적일개치득응용적약물。
Objective:To evaluate clinical efficacy and safety of the Siwu Juanbi decoction on Yuxue Zuzhi type of ankylosing spondylitis. Methods:60 patients were randomly divided into the control group and the treatment group, 30 cases for each;the treatment group was given the Siwu Juanbi decoction; another was given diclofenac, methopterin and sulfasalazine tablets. Clinical indexes, laboratory examination and safety indexes were observed in 3 courses. Results:The total efficacy was 93.3%in the treatment group, and 80.0% in another group (P<0.05); clinical indexes and laboratory examination were improved, the treatment group was better (P<0.05);safety indexes showed significant difference (P<0.05). Conclusion:The Siwu Juanbi decoction could relieve clinical symptoms in patients, control the development of AS, with high safety, and was worthy of promotion.
