中医临床研究
中醫臨床研究
중의림상연구
CLINICAL JOURNAL OF CHINESE MEDICINE
2014年
31期
10-11,20
,共3页
慢性收缩性心力衰竭%补肾温心汤%心肾阳虚%LVEF
慢性收縮性心力衰竭%補腎溫心湯%心腎暘虛%LVEF
만성수축성심력쇠갈%보신온심탕%심신양허%LVEF
Chronic systolic heart failure%The Bushen Wenxin decoction%Xinshen Yangxu%LVEF
目的：观察补肾温心汤治疗慢性收缩性心力衰竭心肾阳虚证的临床疗效。方法：将60例患者随机分为治疗组和对照组两组，每组30例。对照组在一般治疗基础上服用利尿剂、血管紧张素转化酶抑制剂、β受体阻滞剂，必要时予地高辛。治疗组在对照组治疗的基础上加服补肾温心汤150mL/次，2次/d，4周为1个疗程。观察两组治疗前后心功能疗效、心衰疗效、中医证候疗效及LVEF的变化。结果：①两组患者治疗后心功能疗效、心衰疗效、中医证候疗效均优于治疗前，具有显著性差异（P<0.05）；两组间治疗后比较，心功能疗效、心衰疗效、中医证候疗效均显示治疗组优于对照组，具有显著性差异（P<0.05）。②治疗后两组均可以明显改善LVEF，有显著性差异（P<O.05）；两组间治疗后比较也有显著性差异（P<0.05）。结论：补肾温心汤配合西药治疗慢性收缩性心力衰竭心肾阳虚证与单独应用西药治疗相比，能更有效地改善心衰症状、体征，改善中医证候，提高心功能，改善LVEF。
目的：觀察補腎溫心湯治療慢性收縮性心力衰竭心腎暘虛證的臨床療效。方法：將60例患者隨機分為治療組和對照組兩組，每組30例。對照組在一般治療基礎上服用利尿劑、血管緊張素轉化酶抑製劑、β受體阻滯劑，必要時予地高辛。治療組在對照組治療的基礎上加服補腎溫心湯150mL/次，2次/d，4週為1箇療程。觀察兩組治療前後心功能療效、心衰療效、中醫證候療效及LVEF的變化。結果：①兩組患者治療後心功能療效、心衰療效、中醫證候療效均優于治療前，具有顯著性差異（P<0.05）；兩組間治療後比較，心功能療效、心衰療效、中醫證候療效均顯示治療組優于對照組，具有顯著性差異（P<0.05）。②治療後兩組均可以明顯改善LVEF，有顯著性差異（P<O.05）；兩組間治療後比較也有顯著性差異（P<0.05）。結論：補腎溫心湯配閤西藥治療慢性收縮性心力衰竭心腎暘虛證與單獨應用西藥治療相比，能更有效地改善心衰癥狀、體徵，改善中醫證候，提高心功能，改善LVEF。
목적：관찰보신온심탕치료만성수축성심력쇠갈심신양허증적림상료효。방법：장60례환자수궤분위치료조화대조조량조，매조30례。대조조재일반치료기출상복용이뇨제、혈관긴장소전화매억제제、β수체조체제，필요시여지고신。치료조재대조조치료적기출상가복보신온심탕150mL/차，2차/d，4주위1개료정。관찰량조치료전후심공능료효、심쇠료효、중의증후료효급LVEF적변화。결과：①량조환자치료후심공능료효、심쇠료효、중의증후료효균우우치료전，구유현저성차이（P<0.05）；량조간치료후비교，심공능료효、심쇠료효、중의증후료효균현시치료조우우대조조，구유현저성차이（P<0.05）。②치료후량조균가이명현개선LVEF，유현저성차이（P<O.05）；량조간치료후비교야유현저성차이（P<0.05）。결론：보신온심탕배합서약치료만성수축성심력쇠갈심신양허증여단독응용서약치료상비，능경유효지개선심쇠증상、체정，개선중의증후，제고심공능，개선LVEF。
Objective:To observe clinical curative effects of the Bushen Wenxin decoction on chronic systolic heart failure with Xinshen Yangxu. Methods:60 patients were randomly divided into treatment group and control group. On the basis of general treatment, the control group was given the diuretic, angiotensin-converting enzyme inhibitors, β-receptor blocker and digoxin when necessary; the treatment group was added the Bushen Wenxin decoction 150mL, twice a day, for 4 weeks. To observe the curative effect of cardiac function, the curative effect of heart failure, the curative effect of syndromes of TCM and the change of LVEF before and after treatment in two groups. Results: I The curative effect of cardiac function, heart failure, and syndromes of TCM in two groups after treatment were superior than that before treatment, with significant difference, and the treatment group was better (P<0.05). II The LVEF in the two groups can be significantly improved after treatment, with significant difference (P<0.05); difference in two groups with significant difference (P<0.05). Conclusion:Compared with western medicine, the Bushen Wenxin decoction plus western medicine can effectively improve the symptoms, signs of heart failure, syndromes of TCM, cardiac function and LVEF.
