CAJ | 학술논문

目的：对血栓性血小板减少性紫癜（TTP）运用血浆置换联合激素治疗的疗效进行总结。方法对2006年3月～2010年3月由我科确诊的12例TTP患者给予血浆置换联合糖皮质激素治疗。结果本组经治疗后有11例患者症状明显改善，1例死于脑梗死并发急性肾功能衰竭，总有效率为91.7%；血浆置换治疗后5 d血小板恢复正常，住院9～14 d后均好转出院。结论血浆置换联合激素治疗TTP，安全性高，见效快，副作用少，治愈率高，能真正帮助患者减轻病痛，值得临床推广。
목적：대혈전성혈소판감소성자전（TTP）운용혈장치환연합격소치료적료효진행총결。방법대2006년3월～2010년3월유아과학진적12례TTP환자급여혈장치환연합당피질격소치료。결과본조경치료후유11례환자증상명현개선，1례사우뇌경사병발급성신공능쇠갈，총유효솔위91.7%；혈장치환치료후5 d혈소판회복정상，주원9～14 d후균호전출원。결론혈장치환연합격소치료TTP，안전성고，견효쾌，부작용소，치유솔고，능진정방조환자감경병통，치득림상추엄。
Objective To explore and summarize curative effect of plasma exchange combined with hormone therapy for idiopathic thrombocytopenic purpura (TTP) and thrombotic thrombocytopenic. Methods The 12 TTP patients diagnosed from March 2006 to March 2010 were treated with plasma exchange combined with glucocorticoid therapy. Results Af-ter treatment, 11 cases of patients with symptoms were significantly improved, 1 case died of cerebral infarction com-plicated with acute renal failure, the total effective rate was 91.7%. After 5 days plasma exchange treatment, platelet recovery normal. The patients were discharged with a better health condition after hospitalization for 9 to 14 d. Con-clusion Plasma exchange combined with hormone in the treatment of TTP, with higher safety, quicker effect, less side effect, higher cure rate, really help patients to reduce pain, is worth the clinical promotion.