CAJ | 학술논문

目的：探讨利伐沙班与空气波压力联合治疗预防膝关节置换术后下肢深静脉血栓（DVT）的临床效果。方法将136例单侧膝关节置换术患者分为对照组和试验组，每组68例。所有患者术后8h开始给予利伐沙班10mg，每日1次，连续14d；试验组在此基础上开始接受空气波压力治疗，每日3次，每次持续1h，每次间隔6h，连续14d。测量并记录两组患者术后第4、7、14天患肢肿胀程度；观察两组患者住院期间DVT发生情况。结果试验组患者术后第4、7、14天患肢肿胀程度明显轻于对照组（P＜0．05），其DVT发生率也明显低于对照组（2．94％vs．11．77％，P＜0．05）。结论利伐沙班联合空气波压力治疗可减轻膝关节置换术后肢体肿胀程度，降低DVT发生率。
목적：탐토리벌사반여공기파압력연합치료예방슬관절치환술후하지심정맥혈전（DVT）적림상효과。방법장136례단측슬관절치환술환자분위대조조화시험조，매조68례。소유환자술후8h개시급여리벌사반10mg，매일1차，련속14d；시험조재차기출상개시접수공기파압력치료，매일3차，매차지속1h，매차간격6h，련속14d。측량병기록량조환자술후제4、7、14천환지종창정도；관찰량조환자주원기간DVT발생정황。결과시험조환자술후제4、7、14천환지종창정도명현경우대조조（P＜0．05），기DVT발생솔야명현저우대조조（2．94％vs．11．77％，P＜0．05）。결론리벌사반연합공기파압력치료가감경슬관절치환술후지체종창정도，강저DVT발생솔。
Objective To investigate the efficacy of rivaroxaban combined with intermittent pneumatic compression therapy for the prevention of deep vein thrombosis(DVT ) in patients with total knee arthroplasty .Methods Totally 136 patients with total knee arthroplasty were randomly divided into control group and experimental group ,each group with 68 cases .All patients received rivaroxaban 10 mg one time every for 14 days 8 h later after surgery ;experimental group was treated with intermittent pneumatic compression for 1 hour per time with 3 times every for 14 days in addition ,the time interval is 6 h .Thigh swelling was evaluated on 4th ,7th ,14th day after surgery .The prevalence of DVT was assessed during hospitalization .Results The thigh swelling of experi‐mental group after operation was significantly milder than that of control group at 4th ,7th ,14th day (P<0 .05) ,prevalence DVT of experimental group was lower than that of control group (2 .94% vs .11 .77% ,P<0 .05) .Conclusion Rivaroxaban combined with intermittent pneumatic compression could attenuate thigh swelling and reduce the prevalence of DVT after total knee arthroplasty , which is worth of clinical application .