CAJ | 학술논문

目的：探讨急性酒精中毒对失血性休克后早期血气分析的影响。方法随机将40只健康新西兰大耳白兔均分为4组，分别为对照组（A组）、失血性休克组（B组）、急性酒精中毒组（C组）和急性酒精中毒合并失血性休克组（D组），比较四组达到休克所需的放血量和恢复伤前血压的补血补液总量，休克前、休克中、休克复苏后1 h和休克复苏后3h测定动脉血血气分析情况。结果 D组的放血量小于B组，复苏需要更多液体；与A组比较，休克中与复苏后B组、C组及D组pH、PaO2下降，PaCO2、乳酸值升高；与B组比较，D组血清pH，PaO2下降， PaCO2乳酸升高更明显。 B、C、D组pH值、PaCO2、PaO2、乳酸值不同时点和组间PaO2比较，差异具有统计学意义；三组间不同时间pH值、PaCO2、PaO2、乳酸值无交互作用。结论失血性休克后会产生酸中毒，氧分压下降，急性酒精中毒能加重这种变化。
목적：탐토급성주정중독대실혈성휴극후조기혈기분석적영향。방법수궤장40지건강신서란대이백토균분위4조，분별위대조조（A조）、실혈성휴극조（B조）、급성주정중독조（C조）화급성주정중독합병실혈성휴극조（D조），비교사조체도휴극소수적방혈량화회복상전혈압적보혈보액총량，휴극전、휴극중、휴극복소후1 h화휴극복소후3h측정동맥혈혈기분석정황。결과 D조적방혈량소우B조，복소수요경다액체；여A조비교，휴극중여복소후B조、C조급D조pH、PaO2하강，PaCO2、유산치승고；여B조비교，D조혈청pH，PaO2하강， PaCO2유산승고경명현。 B、C、D조pH치、PaCO2、PaO2、유산치불동시점화조간PaO2비교，차이구유통계학의의；삼조간불동시간pH치、PaCO2、PaO2、유산치무교호작용。결론실혈성휴극후회산생산중독，양분압하강，급성주정중독능가중저충변화。
[Abstrcat] Objective To study the effects of acute alcoholism on blood gas analysis in rabbits. Methods Forty New Zelanian big-ear rabbits were divided into four groups randomly. The control group (Group A), the hemorrhagic shock group (Group B), the acute alcoholism group (Group C)and the acute alcoholism and hemorrhagic shock combination group (Group D). Results The volume of blood of Group D was less than Group B. The volume of lipid of Group D needed more. pH and PaO2 of Group D and Group B were decreased than Group A, PaCO2 and lactic acid were risen in the shock and recovered. pH and PaO2 of D Group were decreased than B Group, PaCO2 and lactic acid of D Group were risen than Group B. pH, PaO2, PaCO2 and lactic acid for different time and different group weren’t statistically significant. There was no interaction of pH, PaO2, PaCO2 and lactic acid in different time and different group. Conclusion It will achieved acidosis and decrease in partial pressure of oxygen after hemorrhagic shock. Acute alcoholism can aggravate them.