中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2014年
35期
180-182,186
,共4页
脑卒中%溶栓%预后
腦卒中%溶栓%預後
뇌졸중%용전%예후
Stroke%Thrombolysis%Prognosis
溶栓治疗是改善急性缺血性脑卒中患者临床预后的有效治疗方法,但同时有再灌注损伤、症状性颅内出血、血管再闭塞等并发症,且起病至溶栓治疗时间、神经功能缺损程度、患者年龄、溶栓药物剂量、高血压、糖尿病、抗血小板药物等因素均可能增加溶栓并发症的发生及影响临床预后,在临床应用时应充分考虑影响预后的各种因素,以此指导溶栓治疗。现将临床常见影响溶栓治疗预后的因素进行综述。
溶栓治療是改善急性缺血性腦卒中患者臨床預後的有效治療方法,但同時有再灌註損傷、癥狀性顱內齣血、血管再閉塞等併髮癥,且起病至溶栓治療時間、神經功能缺損程度、患者年齡、溶栓藥物劑量、高血壓、糖尿病、抗血小闆藥物等因素均可能增加溶栓併髮癥的髮生及影響臨床預後,在臨床應用時應充分攷慮影響預後的各種因素,以此指導溶栓治療。現將臨床常見影響溶栓治療預後的因素進行綜述。
용전치료시개선급성결혈성뇌졸중환자림상예후적유효치료방법,단동시유재관주손상、증상성로내출혈、혈관재폐새등병발증,차기병지용전치료시간、신경공능결손정도、환자년령、용전약물제량、고혈압、당뇨병、항혈소판약물등인소균가능증가용전병발증적발생급영향림상예후,재림상응용시응충분고필영향예후적각충인소,이차지도용전치료。현장림상상견영향용전치료예후적인소진행종술。
Thrombolytic therapy is an effective method for improving clinical outcomes for patients with acute ischemic stroke,but at the same time it can bring some complications such as reperfusion injury,symptomatic intracranial hemor-rhage,vascular re-occlusion and so on.A variety factors incuding onset to start of treatment (OTT),degree of neurological impairment,age,thrombolytic dose,hypertension,diabetes,anti-platelet drug may increase thrombolytic complications and affect the prognosis, so in clinical practice the prognostic factors should be fully considered to guide thrombolytic ther-apy.The common factors influencing prognosis of thrombolytic therapy are reviewed now.