中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2014年
35期
28-30
,共3页
黄褐斑%Q开关Nd:YAG 1064 nm激光%茶多酚
黃褐斑%Q開關Nd:YAG 1064 nm激光%茶多酚
황갈반%Q개관Nd:YAG 1064 nm격광%다다분
Chloasma%Q switch Nd:YAG 1064 nm laser%Polyphenols
目的：比较Q开关Nd：YAG 1064 nm激光联合茶多酚与单纯Q开关Nd：YAG 1064 nm激光治疗黄褐斑的临床效果。方法选取2010年2月~2012年10月来本院就诊的67例女性黄褐斑患者，按随机数字表分为观察组(34例)和对照组(33例)。所有患者均采用Q开关1064 nm Nd：YAG激光治疗仪进行治疗，观察组在此基础上同时口服茶多酚胶囊。比较两组的临床疗效、不良反应及复发率。结果观察组治愈率为35.29%，高于对照组的21.21%，观察组总有效率为97.06%，高于对照组的78.79%，差异有统计学意义(P<0.05)。对照组有3例患者激光治疗后出现轻度变态反应，12例治疗中出现风团及红色丘疹，对症处理后消失；观察组口服茶多酚无明显副反应出现。1年后观察组复发率为17.80%，对照组复发率为62.57%。结论单纯采用Q开关1064 nm Nd：YAG激光治疗黄褐斑只能暂时消除皮损的色素，加用茶多酚后，有效解决了黄褐斑的病因问题，提高了黄褐斑的治疗总有效率，降低了复发率。
目的：比較Q開關Nd：YAG 1064 nm激光聯閤茶多酚與單純Q開關Nd：YAG 1064 nm激光治療黃褐斑的臨床效果。方法選取2010年2月~2012年10月來本院就診的67例女性黃褐斑患者，按隨機數字錶分為觀察組(34例)和對照組(33例)。所有患者均採用Q開關1064 nm Nd：YAG激光治療儀進行治療，觀察組在此基礎上同時口服茶多酚膠囊。比較兩組的臨床療效、不良反應及複髮率。結果觀察組治愈率為35.29%，高于對照組的21.21%，觀察組總有效率為97.06%，高于對照組的78.79%，差異有統計學意義(P<0.05)。對照組有3例患者激光治療後齣現輕度變態反應，12例治療中齣現風糰及紅色丘疹，對癥處理後消失；觀察組口服茶多酚無明顯副反應齣現。1年後觀察組複髮率為17.80%，對照組複髮率為62.57%。結論單純採用Q開關1064 nm Nd：YAG激光治療黃褐斑隻能暫時消除皮損的色素，加用茶多酚後，有效解決瞭黃褐斑的病因問題，提高瞭黃褐斑的治療總有效率，降低瞭複髮率。
목적：비교Q개관Nd：YAG 1064 nm격광연합다다분여단순Q개관Nd：YAG 1064 nm격광치료황갈반적림상효과。방법선취2010년2월~2012년10월래본원취진적67례녀성황갈반환자，안수궤수자표분위관찰조(34례)화대조조(33례)。소유환자균채용Q개관1064 nm Nd：YAG격광치료의진행치료，관찰조재차기출상동시구복다다분효낭。비교량조적림상료효、불량반응급복발솔。결과관찰조치유솔위35.29%，고우대조조적21.21%，관찰조총유효솔위97.06%，고우대조조적78.79%，차이유통계학의의(P<0.05)。대조조유3례환자격광치료후출현경도변태반응，12례치료중출현풍단급홍색구진，대증처리후소실；관찰조구복다다분무명현부반응출현。1년후관찰조복발솔위17.80%，대조조복발솔위62.57%。결론단순채용Q개관1064 nm Nd：YAG격광치료황갈반지능잠시소제피손적색소，가용다다분후，유효해결료황갈반적병인문제，제고료황갈반적치료총유효솔，강저료복발솔。
Objective To compare the clinical effect of Q-switched Nd:YAG 1064 nm laser combined with polyphenols and simple Q-switched Nd:YAG 1064 nm laser in treatment of chloasma. Methods 67 female patients with chloasma in our hospital from February 2010 to October 2012 were selected and randomly divided into observation group (34 cases) and control group (33 cases) according to the random number table.All patients were treated with Q-switched 1064 nm Nd:YAG laser,polyphenols capsule was added to the observation group.The clinical efficacy,adverse reactions, relapse rate between the two groups was analyzed. Results The cure rate and total effective rate of the observation group was 35.29% and 97.06%,the control group was 21.21% and 78.79%,the total effective rate of the observation group was higher than that of the control group,the difference was significant (P<0.05).There were 3 patients with mild allergic reactions,12 cases with red papules appear and disappear after symptomatic treatment in the control group after laser treatment.Observation group had no obvious side effects appear after oral polyphenols.The recurrence rate of ob-servation group after one year was 17.80%,the control group was 62.57%. Conclusion Simple Q-switch 1064 nm Nd:YAG laser in treatment of chloasma can only temporarily remove pigmented skin lesions,and after the addition of the polyphenols,effectively solve the cause of chloasma,increase the efficiency,reduce the recurrence rate.
