CAJ | 학술논문

目的：分析糖尿病患者合并医院获得性肺炎的诊断与治疗。方法选取糖尿病合并医院获得性肺炎患者42例，分析糖尿病合并医院获得性肺炎患者42例的感染因素情况以及主要致病菌和常见的治疗药物敏感性情况。结果存在肺部基础疾病、有吸烟史、住院时间在30d以上及使用抗生素治疗患者感染的发生率明显高于没有肺部基础疾病、没有吸烟史、住院时间不足30 d及未使用抗生素治疗患者感染的发生率（P<0.05）；且医院获得性肺炎致病菌主要有大肠埃希菌、铜绿假单胞菌、白色念珠菌、金黄色葡萄球菌以及肺炎克雷伯菌等，发生革兰氏阴性菌感染的患者对于阿米卡星和亚胺培南的敏感性明显较高，而对万古霉素的敏感性较高的细菌则为金黄色葡萄球菌，差异均有统计学意义（P＜0.05）。结论糖尿病患者合并医院获得性肺炎的诊断与治疗意义重大，确诊患者的致病菌并对其进行针对性治疗，可提高临床疗效。
목적：분석당뇨병환자합병의원획득성폐염적진단여치료。방법선취당뇨병합병의원획득성폐염환자42례，분석당뇨병합병의원획득성폐염환자42례적감염인소정황이급주요치병균화상견적치료약물민감성정황。결과존재폐부기출질병、유흡연사、주원시간재30d이상급사용항생소치료환자감염적발생솔명현고우몰유폐부기출질병、몰유흡연사、주원시간불족30 d급미사용항생소치료환자감염적발생솔（P<0.05）；차의원획득성폐염치병균주요유대장애희균、동록가단포균、백색념주균、금황색포도구균이급폐염극뢰백균등，발생혁란씨음성균감염적환자대우아미잡성화아알배남적민감성명현교고，이대만고매소적민감성교고적세균칙위금황색포도구균，차이균유통계학의의（P＜0.05）。결론당뇨병환자합병의원획득성폐염적진단여치료의의중대，학진환자적치병균병대기진행침대성치료，가제고림상료효。
Objective To analyze and explore the diagnosis and hospital acquired pneumonia.Methods Clinical datas of 42 patients with diabetes and HAP in our hospital were retrospectively analyzed, infection condition,the main pathogenic bacteria and common drug susceptibility of these patients were analyzed.Results The infection rate of patients with lung underlying disease, smoking history, more than 30d in hospital and treatment of antibiotics were signiifcantly higher than patients without lung underlying disease, smoking history, more than 30d in hospital and treatment of antibiotics ;and the main pathogenic bacteria of HAP were escherichia coli, pseudomonas aeruginosa, candida albicans, staphylococcus aureus and klebsiella pneumoniae, patients infected by gram negative bacteria had higher susceptibility for amikacin and imipenem, and staphylococcus aureus had higher susceptibility for vancomycin, differences were statistically signiifcant (P<0.05).Conclusion It can improve the clinical efifcacy that ifnd the pathogenic bacteria and target treatment for patients with diabetes and HAP.