CAJ | 학술논문

目的：研究医用一次性聚氯乙烯（PVC）连接管对多种药物的吸附性，为临床一次性连接管的选择提供参考。方法将硝酸甘油、尼莫地平、单硝酸异山梨酯等6种药物分别配成临床输注浓度，通过吸光度试验测试流经连接管前后药物浓度，计算得出6种药物不同时间段的吸附率。结果医用一次性 PVC 连接管对不同药物的吸附性不同，连接管对尼莫地平具有很强的吸附性，最高可达29.6%。结论 PVC 连接管的吸附性与药液的酸碱性没有明显关系；PVC连接管对部分药物具有极强的吸附作用，应引起临床使用的高度重视。
목적：연구의용일차성취록을희（PVC）련접관대다충약물적흡부성，위림상일차성련접관적선택제공삼고。방법장초산감유、니막지평、단초산이산리지등6충약물분별배성림상수주농도，통과흡광도시험측시류경련접관전후약물농도，계산득출6충약물불동시간단적흡부솔。결과의용일차성 PVC 련접관대불동약물적흡부성불동，련접관대니막지평구유흔강적흡부성，최고가체29.6%。결론 PVC 련접관적흡부성여약액적산감성몰유명현관계；PVC련접관대부분약물구유겁강적흡부작용，응인기림상사용적고도중시。
Objective To investigate the absorptivity of medical disposable PVC connection tube to various drugs, as a reference for clinical choice of disposable PVC connection tube. Methods Solution of 6 kinds of drugs, such as nitroglycerin, nimodipine and isosorbide mononitrate,were prepared separately as per actual concentration needed by the clinic. Drug concentrations before and after through the connection tube were measured by absorbance experiment and eventually calculated absorption rate of 6 kinds of drugs in different time. Results The various drugs have different absorption rate and nimodipine gets a rather high value which can be up to 29.6%. Conclusion The absorptivity of PVC connection tube has little relation to acid-base property. They have marked absorptivity to part of drugs. High attention from the clinic should be paid to the difference.