放射学实践
放射學實踐
방사학실천
RADIOLOGIC PRACTICE
2014年
12期
1443-1446,1447
,共5页
张喜荣%黄小华%董国礼%刘念
張喜榮%黃小華%董國禮%劉唸
장희영%황소화%동국례%류념
胰腺%体层摄影术,X 线计算机%灌注成像%肝肿瘤%血流动力学
胰腺%體層攝影術,X 線計算機%灌註成像%肝腫瘤%血流動力學
이선%체층섭영술,X 선계산궤%관주성상%간종류%혈류동역학
Pancreas%Tomography,X-ray computed%Perfusion imaging%Liver neoplasms%Hemodynamics
目的:探讨基于原发性肝癌血流再分布状态下的胰腺血流灌注特点。方法:90例患者按纳入标准分为 A、B、C 三组,其中 A 组(正常对照组)49例,B 组(原发性肝癌组)21例,C 组(原发性肝癌合并门脉癌栓组)20例。所有患者均行常规 CT 平扫和增强扫描以及 CT 灌注成像。测量每例患者胰腺实质的灌注参数值,包括血流量(BF)、血容量(BV)、表面通透性(PS)和平均时间(MTT)。对3组间各灌注参数值的差异进行统计学分析(方差分析法或秩和检验)。结果:A、B、C 三组中胰腺的 BF、BV、PS 和 MTT 的测量值:A 组分别为(159.60±68.14)mL/(100g·min)、(49.00±18.89)mL/100g、(221.52±51.55)mL/(100g·min)和(28.16±7.25)s;B 组依次为(106.48±24.63)mL/(100g·min)、(37.63±21.67)mL/100g、(232.07±78.38)mL/(100g·min)和(30.33±6.83)s;C 组依次为(105.14±26.13)mL/(100g·min)、(39.44±18.65)mL/100g、(212.48±43.53)mL/(100g·min)和(25.78±8.12)s。三组中 A 组的 BF 值与 B、C 组之间的差异具有统计学意义(Z 值分别为-4.428和-4.722,P <0.05);三组间 BV、MTT 和 PS 值的差异无统计学意义(P >0.05)。结论:原发性肝癌无论有无门静脉癌栓形成,都可能导致肝脏周围血流再分布并进而影响胰腺的血流灌注,使胰腺的血流量降低;MSCT 灌注成像能较敏感地显示胰腺血流灌注的改变。
目的:探討基于原髮性肝癌血流再分佈狀態下的胰腺血流灌註特點。方法:90例患者按納入標準分為 A、B、C 三組,其中 A 組(正常對照組)49例,B 組(原髮性肝癌組)21例,C 組(原髮性肝癌閤併門脈癌栓組)20例。所有患者均行常規 CT 平掃和增彊掃描以及 CT 灌註成像。測量每例患者胰腺實質的灌註參數值,包括血流量(BF)、血容量(BV)、錶麵通透性(PS)和平均時間(MTT)。對3組間各灌註參數值的差異進行統計學分析(方差分析法或秩和檢驗)。結果:A、B、C 三組中胰腺的 BF、BV、PS 和 MTT 的測量值:A 組分彆為(159.60±68.14)mL/(100g·min)、(49.00±18.89)mL/100g、(221.52±51.55)mL/(100g·min)和(28.16±7.25)s;B 組依次為(106.48±24.63)mL/(100g·min)、(37.63±21.67)mL/100g、(232.07±78.38)mL/(100g·min)和(30.33±6.83)s;C 組依次為(105.14±26.13)mL/(100g·min)、(39.44±18.65)mL/100g、(212.48±43.53)mL/(100g·min)和(25.78±8.12)s。三組中 A 組的 BF 值與 B、C 組之間的差異具有統計學意義(Z 值分彆為-4.428和-4.722,P <0.05);三組間 BV、MTT 和 PS 值的差異無統計學意義(P >0.05)。結論:原髮性肝癌無論有無門靜脈癌栓形成,都可能導緻肝髒週圍血流再分佈併進而影響胰腺的血流灌註,使胰腺的血流量降低;MSCT 灌註成像能較敏感地顯示胰腺血流灌註的改變。
목적:탐토기우원발성간암혈류재분포상태하적이선혈류관주특점。방법:90례환자안납입표준분위 A、B、C 삼조,기중 A 조(정상대조조)49례,B 조(원발성간암조)21례,C 조(원발성간암합병문맥암전조)20례。소유환자균행상규 CT 평소화증강소묘이급 CT 관주성상。측량매례환자이선실질적관주삼수치,포괄혈류량(BF)、혈용량(BV)、표면통투성(PS)화평균시간(MTT)。대3조간각관주삼수치적차이진행통계학분석(방차분석법혹질화검험)。결과:A、B、C 삼조중이선적 BF、BV、PS 화 MTT 적측량치:A 조분별위(159.60±68.14)mL/(100g·min)、(49.00±18.89)mL/100g、(221.52±51.55)mL/(100g·min)화(28.16±7.25)s;B 조의차위(106.48±24.63)mL/(100g·min)、(37.63±21.67)mL/100g、(232.07±78.38)mL/(100g·min)화(30.33±6.83)s;C 조의차위(105.14±26.13)mL/(100g·min)、(39.44±18.65)mL/100g、(212.48±43.53)mL/(100g·min)화(25.78±8.12)s。삼조중 A 조적 BF 치여 B、C 조지간적차이구유통계학의의(Z 치분별위-4.428화-4.722,P <0.05);삼조간 BV、MTT 화 PS 치적차이무통계학의의(P >0.05)。결론:원발성간암무론유무문정맥암전형성,도가능도치간장주위혈류재분포병진이영향이선적혈류관주,사이선적혈류량강저;MSCT 관주성상능교민감지현시이선혈류관주적개변。
Objectire:To explore the blood flow perfusion characteristics of pancreas based on redistribution of blood flow caused by primary liver cancer.Methods:According to the inclusion criteria,90 patients with normal pancreas were se-lected and divided into three groups,of which 49 cases were in group A (control group),21 patients with primary hepatic carcinoma (PHC)in group B,and 20 PHC patients with tumor embolus in portal vein (PVTE)were in group C.All the pa-tients underwent conventional pre-contrast and post-contrast CT scan,and then CT perfusion imaging.The perfusion para-meters of pancreas were measured,including mean blood flow (BF),blood volume (BV),permeability surface (PS)and mean transit time (MTT).The difference of the four perfusion parameters in 3 groups was analyzed statistically with variance analysis or rank sum test.Results:The mean values of BF,BV,PS and MTT in Group A were (159.60 ± 68.14)mL/(100g·min),(49.00±18.89)mL/100g,(221.52 ±51.55)mL/(100g·min)and (28.16 ±7.25)s,respectively;in Group B were (106.48±24.63)mL/(100g·min),(37.63±21.67)mL/100g,(232.07±78.38)mL/(100g·min),and (30.33±6.83)s, respectively;in Group C were (105.14±26.13)mL/(100g·min),(39.44±18.65)mL/100g,(212.48±43.53)mL/(100g· min)and (25.78±8.12)s,respectively.The BF of group A showed statistical difference in comparison with that of group B and C (Z =-4.428 and -4.722 respectively,P <0.05).The BV,MTT and PS showed no statistic difference in the three groups (P >0.05).Conclusion:Redistribution of blood flow in liver caused by PHC with or without PVTE may change the perfusion status of pancreas with reduction of blood flow;CT perfusion imaging is very useful for detecting the perfusion change of pancreas with high sensitivity.