当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2014年
35期
19-21
,共3页
膀胱癌%液基细胞学%核基质蛋白22%膀胱肿瘤抗原
膀胱癌%液基細胞學%覈基質蛋白22%膀胱腫瘤抗原
방광암%액기세포학%핵기질단백22%방광종류항원
Bladder carcinoma%Liquid-based cytology%Unclear matrix 22%Bladder tumor antigen
目的：探讨液基细胞学、液基细胞学联合核基质蛋白22（NMP 22）、膀胱肿瘤抗原（BTA）检测对膀胱癌诊断的价值。方法对收治的196例膀胱癌疑似及随访患者的尿液进行液基细胞学检查，对其中68例细胞学诊断阳性和非典型标本同时进行NMP 22、BTA检测，将结果与组织病理学诊断结果对比，评估它们对膀胱癌的诊断价值。结果液基细胞学、液基联合NMP 22、BTA和三者联合检测的敏感度分别为72.9%、83.3%、87.5%、93.8%，组间比较差异有统计学意义（P＜0.05）；特异度分别为95.0%、80.0%、85.0%、90.0%，组间比较差异无统计学意义。结论液基细胞学联合NMP 22或（和） BTA检测可进一步提高对膀胱癌的敏感度，并无创伤性诊断方法。
目的：探討液基細胞學、液基細胞學聯閤覈基質蛋白22（NMP 22）、膀胱腫瘤抗原（BTA）檢測對膀胱癌診斷的價值。方法對收治的196例膀胱癌疑似及隨訪患者的尿液進行液基細胞學檢查，對其中68例細胞學診斷暘性和非典型標本同時進行NMP 22、BTA檢測，將結果與組織病理學診斷結果對比，評估它們對膀胱癌的診斷價值。結果液基細胞學、液基聯閤NMP 22、BTA和三者聯閤檢測的敏感度分彆為72.9%、83.3%、87.5%、93.8%，組間比較差異有統計學意義（P＜0.05）；特異度分彆為95.0%、80.0%、85.0%、90.0%，組間比較差異無統計學意義。結論液基細胞學聯閤NMP 22或（和） BTA檢測可進一步提高對膀胱癌的敏感度，併無創傷性診斷方法。
목적：탐토액기세포학、액기세포학연합핵기질단백22（NMP 22）、방광종류항원（BTA）검측대방광암진단적개치。방법대수치적196례방광암의사급수방환자적뇨액진행액기세포학검사，대기중68례세포학진단양성화비전형표본동시진행NMP 22、BTA검측，장결과여조직병이학진단결과대비，평고타문대방광암적진단개치。결과액기세포학、액기연합NMP 22、BTA화삼자연합검측적민감도분별위72.9%、83.3%、87.5%、93.8%，조간비교차이유통계학의의（P＜0.05）；특이도분별위95.0%、80.0%、85.0%、90.0%，조간비교차이무통계학의의。결론액기세포학연합NMP 22혹（화） BTA검측가진일보제고대방광암적민감도，병무창상성진단방법。
Objective To explore the value of liquid-based cytology ,united urinary liquid-based cytology, unclear matrix protein 22(NMP 22) and bladder tumor antigen (BTA) in the diagnosis of the urinary carcinoma of the bladder. Methods 68 cases of positive cytology were tested the NMP-22 and BTA with comparison of histology in the 196 cases with urinary liquid-based cytology test. Results The sensitive rate in liquid-based cytology, liquid-based cytology united NMP 22, liquid-based cytology united BTA and the united three indexes were 72.9%, 83.3%, 87.5%and 93.8%accordingly and there were statistic diference(P<0.05). The specific rate in liquid-based cytology, liquid-based cytology united NMP 22 , liquid-based cytology united BTA and the united three indexes were 95.0%, 80.0%, 85.0%and 90.0%accordingly and there were no statistic diference. Conclusion Urinary liquid-based cytology united the NMP 22 and BTA test can impove the diagnosis sensitive rate of the urinary carcinoma of the bladder with no injury to the patient.
