CAJ | 학술논문

目的：探讨晚期肺鳞癌血清鳞癌相关抗原(SCC-Ag)检测的临床价值。方法80例肺癌患者为研究对象，其中鳞癌50例，腺癌14例，小细胞肺癌(SCLC)11例，大细胞肺癌(LCLC)5例，另选45例良性病变患者，对所有患者进行SCC-Ag检测。结果肺鳞癌阳性率为68.00%，肺腺癌阳性率14.29%， SCLC阳性率18.18%， LCLC阳性率20.00%，对照组2.22%。经手术前后动态观察显示，根治术后SCC-Ag可在3 d内转阴，与其他术式比较差异有统计学意义(P<0.05)。结论SCC-Ag为肺鳞癌特殊标记物，是对患者手术效果与远期预后进行预测的重要参考指标。
목적：탐토만기폐린암혈청린암상관항원(SCC-Ag)검측적림상개치。방법80례폐암환자위연구대상，기중린암50례，선암14례，소세포폐암(SCLC)11례，대세포폐암(LCLC)5례，령선45례량성병변환자，대소유환자진행SCC-Ag검측。결과폐린암양성솔위68.00%，폐선암양성솔14.29%， SCLC양성솔18.18%， LCLC양성솔20.00%，대조조2.22%。경수술전후동태관찰현시，근치술후SCC-Ag가재3 d내전음，여기타술식비교차이유통계학의의(P<0.05)。결론SCC-Ag위폐린암특수표기물，시대환자수술효과여원기예후진행예측적중요삼고지표。
Objective To investigate the clinical value of serum squamous cell carcinoma related antigen (SCC-Ag) detection in advanced lung squamous cell carcinoma.Methods Among the study subjects as 80 lung cancer patients, there were 50 cases with squamous cell carcinoma, 14 cases with adenocarcinoma, 11 cases with small cell lung cancer (SCLC), and 5 cases with large cell lung cancer (LCLC). Another 45 patients with benign lesion were selected as well. All the patients received SCC-Ag detection.Results The positive rate of lung squamous cell carcinoma was 68.00%, that of lung adenocarcinoma was 14.29%, that of SCLC was 18.18%, that of LCLC was 20.00%, and that in the control group was 2.22%. The result of dynamic observation before and after surgery showed that SCC-Ag turned to be negative within 3 d after surgery, and it had statistically significant difference with other methods (P<0.05).Conclusion SCC-Ag is the specific marker for lung squamous cell carcinoma, and it provides an important reference index for the prediction of surgery effect and long-term prognosis for patients.