CAJ | 학술논문

目的：B型钠尿肽（ proBNPⅡ）联合血清降钙素原（ PCT）在心功能不全及疑似合并肺部细菌感染患者诊断中的价值。方法：慢性心功能不全、肺部细菌感染、慢性心功能不全合并肺部细菌感染者各30例，同时测定PCT及proBNPⅡ。结果：30例肺部细菌感染患者PCT阳性29例，阳性率96.67%，同时测定proBNPⅡ，阳性3例，阳性率10.00%；30例慢性心功能不全急性发作患者PCT阳性2例，阳性率6.67%，同时测定proBNPⅡ，患者proBNPⅡ阳性30例，阳性率100.00%；30例慢性心功能不全合并肺部细菌感染者，PCT及proBNPⅡ阳性率均达100.00%。结论：PCT及proBNPⅡ联合检测可作为早期快速鉴别慢性心功能不全急性发作是否伴有肺部细菌感染的实验室指标，指导临床治疗方案及抗生素的合理应用。
목적：B형납뇨태（ proBNPⅡ）연합혈청강개소원（ PCT）재심공능불전급의사합병폐부세균감염환자진단중적개치。방법：만성심공능불전、폐부세균감염、만성심공능불전합병폐부세균감염자각30례，동시측정PCT급proBNPⅡ。결과：30례폐부세균감염환자PCT양성29례，양성솔96.67%，동시측정proBNPⅡ，양성3례，양성솔10.00%；30례만성심공능불전급성발작환자PCT양성2례，양성솔6.67%，동시측정proBNPⅡ，환자proBNPⅡ양성30례，양성솔100.00%；30례만성심공능불전합병폐부세균감염자，PCT급proBNPⅡ양성솔균체100.00%。결론：PCT급proBNPⅡ연합검측가작위조기쾌속감별만성심공능불전급성발작시부반유폐부세균감염적실험실지표，지도림상치료방안급항생소적합리응용。
Objective To explore the diagnostic value of B-type natriuretic peptide( BNP)combined with procalcitonin( PCT)in car-diac insufficiency patients with suspected pulmonary infections. Method Patients with chronic cardiac insufficiency(n=30),patients with pulmonary bacterial infection( n=30 ),and patients with chronic heart failure complicated with pulmonary bacterial infection( n=30 ) were enrolled in the study,all monitored PCT and proBNP II simultaneously. Results In patients with pulmonary bacterial infection,the pos-itive rate of PCT was 96. 67%(29 case),of proBNPⅡ was 10%(3 cases). In patients with chronic cardiac insufficiency,the positive rate of PCT was 6. 67%(2 case),of proBNPⅡwas 100%(30 cases). In patients with chronic heart failure complicated with pulmonary bacteri-al infection,the positive rate of PCT was 100%(30 case),of proBNPⅡwas 100%(30 cases). Conclusion Combined PCT and proBNPⅡmay contribute to identify whether chronic heart failure complicated with pulmonary bacterial infection or not early and rapidly,which may be helpful for reasonable decision of clinical treatment and application of antibiotics.