CAJ | 학술논문

目的：观察早期目标导向治疗（ EGDT）糖尿病合并脓毒性休克患者的临床效果。方法：将48例糖尿病合并脓毒性休克患者随机分为治疗组（ n＝24）和对照组（ n＝24），治疗组采用EGDT，对照组采用常规复苏治疗。观察两组治疗后血流动力学指标、氧代谢指标、血糖控制、MODS发生率、28 d病死率。结果：两组患者入选时的病情差异无统计学意义（ P>0.05），治疗组治疗后6 h及24 h的血流动力学指标、氧代谢指标、血糖控制水平、MODS发生率、28 d病死率与对照组比较差异有统计学意义（ P<0.05）。结论：EGDT能显著改善糖尿病合并脓毒性休克患者预后。
목적：관찰조기목표도향치료（ EGDT）당뇨병합병농독성휴극환자적림상효과。방법：장48례당뇨병합병농독성휴극환자수궤분위치료조（ n＝24）화대조조（ n＝24），치료조채용EGDT，대조조채용상규복소치료。관찰량조치료후혈류동역학지표、양대사지표、혈당공제、MODS발생솔、28 d병사솔。결과：량조환자입선시적병정차이무통계학의의（ P>0.05），치료조치료후6 h급24 h적혈류동역학지표、양대사지표、혈당공제수평、MODS발생솔、28 d병사솔여대조조비교차이유통계학의의（ P<0.05）。결론：EGDT능현저개선당뇨병합병농독성휴극환자예후。
Objective To observe the early“goal-directed therapy”( EGDT)on diabetic clinical effect of septic shock. Method 48 cases of diabetic patients with septic shock were randomly divided into treatment group(n=24)and the control group(n=24),the treat-ment group was given the early goal-directed therapy,the control group was given conventional recovery treatment. To observe the hemody-namic indexes of the two groups after treatment,the metabolism of oxygen index,blood sugar control 28 days,MODS incidence,mortali-ty. Results Two groups of patients was no statistical difference( P>0. 05),the treatment group after treatment 6 h and 24 h,hemodynamic index,oxygen metabolism index,blood sugar control level 28 days,MODS incidence,mortality compared with the control group were statisti-cally difference( P<0. 05 ). Conclusion Early goal-directed therapy can significantly improve the prognosis of patients with diabetes complicating septic shock.