CAJ | 학술논문

目的：探讨慢性萎缩性胃炎的中医证型分布与胃黏膜病理改变程度、幽门螺杆菌（ H．pylori）感染的相关性。方法将431例慢性萎缩性胃炎患者辨证分为6个证型：肝胃气滞证59例，肝胃郁热证35例，脾胃虚弱证168例，脾胃湿热证52例，胃阴不足证24例，胃络瘀血证93例。分析各证型与胃黏膜病理改变程度、幽门螺杆菌感染的关系。结果（1）各中医证型在不同程度胃粘膜萎缩分布上存在显著性差异（ P＜0．05），其中肝胃气滞证与脾胃虚弱证、胃络瘀血证比较差异均有统计学意义（P＜0．0033）；（2）各中医证型在不同程度肠化生分布上存在显著性差异（P＜0．05），其中，肝胃气滞证与胃络瘀血证比较存在显著性差异（P＜0．0033）；（3）各中医证型在不同程度异型增生分布上差异无显著性意义（P＞0．05）。结论中医证型分布与胃黏膜病理改变程度、H．pylori感染有一定的相关性。
목적：탐토만성위축성위염적중의증형분포여위점막병리개변정도、유문라간균（ H．pylori）감염적상관성。방법장431례만성위축성위염환자변증분위6개증형：간위기체증59례，간위욱열증35례，비위허약증168례，비위습열증52례，위음불족증24례，위락어혈증93례。분석각증형여위점막병리개변정도、유문라간균감염적관계。결과（1）각중의증형재불동정도위점막위축분포상존재현저성차이（ P＜0．05），기중간위기체증여비위허약증、위락어혈증비교차이균유통계학의의（P＜0．0033）；（2）각중의증형재불동정도장화생분포상존재현저성차이（P＜0．05），기중，간위기체증여위락어혈증비교존재현저성차이（P＜0．0033）；（3）각중의증형재불동정도이형증생분포상차이무현저성의의（P＞0．05）。결론중의증형분포여위점막병리개변정도、H．pylori감염유일정적상관성。
Objective To discuss the relationship among different TCM syndrome of CAG , relevant pathological changes and Helicobacter pylori infection .Methods 431 CAG patients were divided into 6 kinds of TCM syndromes , i.e.59 cases of liver and stomach qi stagnation syndrome , 35 cases of stagnated heat of liver and stomach syndrome , 168 cases of spleen-stomach deficiency syndrome , 52 cases of spleen-stomach damp heat syndrome , 24 cases of stomach yin deficiency syndrome and 93 cases of stomach merid-ian of blood stasis syndrome .To analysis the relationship among different syndrome , relevant pathological changes and Helicobacter pylori infection .Results (1)In the distribution of different degrees of atrophy , there were statistically significant differences among the six syndromes (P<0.05).Differences were statis-tically significant when Liver and stomach qi stagnation syndrome compared with spleen-stomach deficiency syndrome and stomach meridian of blood stasis syndrome (P<0.0033).(2) In the distribution of differ-ent degrees of intestinal metaplasia , there were statistically significant differences among the six syndromes (P<0.05).Difference was statistically significant when Liver and stomach qi stagnation syndrome com-pared with stomach meridian of blood stasis syndrome (P<0.0033).(3) In the distribution of different degrees of dysplasia , there were no statistically significant differences among the six syndromes ( P >0.05).Conclusion There were correlation among TCM syndromes , pathological changes and Helicobacter pylori infection .