中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
32期
37-39,40
,共4页
硫辛酸%前列地尔%糖尿病%心脏自主神经病变%心率变异性
硫辛痠%前列地爾%糖尿病%心髒自主神經病變%心率變異性
류신산%전렬지이%당뇨병%심장자주신경병변%심솔변이성
Lipoic acid%Alprostadil%Diabetes mellitus%Autonomic neuropathy%Heart rate variability
目的:分析与研究硫辛酸联合前列地尔对糖尿病心脏自主神经病变患者心率变异性的影响。方法:对本院2010年6月-2013年10月期间收治的60例糖尿病合并心脏自主神经病变患者的临床资料进行回顾性分析,将60例患者划分为研究组与对照组,两组各30例;对照组行常规综合治疗,研究组在常规综合治疗的基础上,行硫辛酸联合前列地尔治疗。对比两组治疗之前与治疗之后心率变异性指标。结果:两组患者血糖、TG、TC均呈明显下降趋势,与治疗前相比,差异具有统计学意义(P<0.05),HDL-C、LDL-C与治疗前相比,差异无统计学意义(P>0.05),研究组治疗后SDANN、SDNN、PNN50、rMSSD均比对照组高,差异具有统计学意义(P<0.05)。研究组患者的治疗有效率为86.67%,较对照组治疗有效率60%高,差异具有统计学意义(P<0.05)。结论:硫辛酸联合前列地尔治疗糖尿病合并心脏自主神经病变具有显著效果,值得在临床治疗中推广使用。
目的:分析與研究硫辛痠聯閤前列地爾對糖尿病心髒自主神經病變患者心率變異性的影響。方法:對本院2010年6月-2013年10月期間收治的60例糖尿病閤併心髒自主神經病變患者的臨床資料進行迴顧性分析,將60例患者劃分為研究組與對照組,兩組各30例;對照組行常規綜閤治療,研究組在常規綜閤治療的基礎上,行硫辛痠聯閤前列地爾治療。對比兩組治療之前與治療之後心率變異性指標。結果:兩組患者血糖、TG、TC均呈明顯下降趨勢,與治療前相比,差異具有統計學意義(P<0.05),HDL-C、LDL-C與治療前相比,差異無統計學意義(P>0.05),研究組治療後SDANN、SDNN、PNN50、rMSSD均比對照組高,差異具有統計學意義(P<0.05)。研究組患者的治療有效率為86.67%,較對照組治療有效率60%高,差異具有統計學意義(P<0.05)。結論:硫辛痠聯閤前列地爾治療糖尿病閤併心髒自主神經病變具有顯著效果,值得在臨床治療中推廣使用。
목적:분석여연구류신산연합전렬지이대당뇨병심장자주신경병변환자심솔변이성적영향。방법:대본원2010년6월-2013년10월기간수치적60례당뇨병합병심장자주신경병변환자적림상자료진행회고성분석,장60례환자화분위연구조여대조조,량조각30례;대조조행상규종합치료,연구조재상규종합치료적기출상,행류신산연합전렬지이치료。대비량조치료지전여치료지후심솔변이성지표。결과:량조환자혈당、TG、TC균정명현하강추세,여치료전상비,차이구유통계학의의(P<0.05),HDL-C、LDL-C여치료전상비,차이무통계학의의(P>0.05),연구조치료후SDANN、SDNN、PNN50、rMSSD균비대조조고,차이구유통계학의의(P<0.05)。연구조환자적치료유효솔위86.67%,교대조조치료유효솔60%고,차이구유통계학의의(P<0.05)。결론:류신산연합전렬지이치료당뇨병합병심장자주신경병변구유현저효과,치득재림상치료중추엄사용。
Objective:To analyze and research the lipoic acid on the aforementioned,heart rate variability in patients with diabetic cardiac autonomic neuropathy.Method:In our hospital from June 2010 to October 2010 clinical data of 60 cases of diabetic cardiac autonomic neuropathy were retrospectively analyzed,60 patients were divided into research group and control group,each group of 30 cases;control group routine comprehensive treatment,the team on the basis of routine comprehensive treatment,joint top line lipoic acid to treatment.Compared the two groups before treatment and after treatment of heart rate variability index.Result:Two groups of patients were in significantly lower the blood glucose,TG, TC,compared with the treatment of the front,the differences were statistically significant(P<0.05),HDL-C,LDL-C compared with before treatment,no significant difference(P>0.05),the team after treatment SDANN,SDNN,PNN50, rMSSD were higher in control group,the differences were statistically significant(P<0.05).Team treatment effective rate of 86.67%than the control group in patients with high effective rate was 60%,the difference were statistically significant (P<0.05).Conclusion:Lipoic acid united front,treatment of diabetic cardiac autonomic neuropathy has significant effect,is worth popularizing in clinical treatment.