CAJ | 학술논문

背景：坐骨结节滑囊炎被认识长久，但其治疗手段仍保留在40年前的封闭及手术等方法。目的：分析富血小板血浆注射治疗坐骨结节滑囊炎的疗效。方法：收集15例坐骨结节滑囊炎患者资料。所有患者双侧同时接受富血小板血浆(n=10例，共20侧)或封闭(n=5例，共10侧)注射治疗。随访6-14个月，采用目测类比评分法、治疗满意度评分及复发率进行评估，比较这两种治疗方法在各观察时间点的评分，评估治疗效果。结果与结论：在目测类比评分方面，富血小板血浆组和封闭组综合各时间点的结果比较差异无显著性意义(F=0.219，P=0.643)；分别在各个时间点两组间比较，富血小板血浆注射的疼痛评分在短期内(治疗后1周内)高于封闭注射，但长期随访的疼痛评分低于封闭组。在总体满意度、疗效和不良反应评分方面，富血小板血浆注射在短期内(尤其是治疗后1周)的评分不如封闭注射，但持久的长期评分却高于封闭注射。在方便性评分方面，两者差异无统计学意义。末次随访富血小板血浆注射治疗的复发率较封闭注射低。分析结果说明对于坐骨结节滑囊炎的治疗，富血小板血浆注射和封闭注射均可缓解疼痛，封闭注射的短期疗效更好，尤其是在治疗后1周内，但其长期疗效不佳，而富血小板血浆注射起效缓和，但疗效持久、复发率更低。
배경：좌골결절활낭염피인식장구，단기치료수단잉보류재40년전적봉폐급수술등방법。목적：분석부혈소판혈장주사치료좌골결절활낭염적료효。방법：수집15례좌골결절활낭염환자자료。소유환자쌍측동시접수부혈소판혈장(n=10례，공20측)혹봉폐(n=5례，공10측)주사치료。수방6-14개월，채용목측류비평분법、치료만의도평분급복발솔진행평고，비교저량충치료방법재각관찰시간점적평분，평고치료효과。결과여결론：재목측류비평분방면，부혈소판혈장조화봉폐조종합각시간점적결과비교차이무현저성의의(F=0.219，P=0.643)；분별재각개시간점량조간비교，부혈소판혈장주사적동통평분재단기내(치료후1주내)고우봉폐주사，단장기수방적동통평분저우봉폐조。재총체만의도、료효화불량반응평분방면，부혈소판혈장주사재단기내(우기시치료후1주)적평분불여봉폐주사，단지구적장기평분각고우봉폐주사。재방편성평분방면，량자차이무통계학의의。말차수방부혈소판혈장주사치료적복발솔교봉폐주사저。분석결과설명대우좌골결절활낭염적치료，부혈소판혈장주사화봉폐주사균가완해동통，봉폐주사적단기료효경호，우기시재치료후1주내，단기장기료효불가，이부혈소판혈장주사기효완화，단료효지구、복발솔경저。
BACKGROUND:Ischiogluteal bursitis has been recognized for a long time, but its treatment stil limits to local blocking injection and surgery methods that were developed 40 years ago. OBJECTIVE:To observe the efficacy of platelet-rich plasma on ischiogluteal bursitis. METHODS:Data of 15 patients with ischiogluteal bursitis were colected. Al the patients with ischiogluteal bursitis were treated with bilateral platelet-rich plasma (n=10) or local blocking injection (n=5). Patients’ outcomes were assessed by visual analogue scale, the Treatment Satisfaction Questionnaire for Medication (TSQM) Version II and recurrence rate. The folow-up time was from 6 to 14 months. RESULTS AND CONCLUSION: There was no statistical difference in visual analogue scale score between the platelet-rich plasma group and local blocking group (F=0.219,P=0.643), but the score of visual analogue scale in the platelet-rich plasma group was higher during short-term folow-up (within 1 week after treatment), but lower in the long-term folow-up. In the aspects of overal satisfaction score, clinical effectiveness and side effects, the platelet-rich plasma group was inferior to the local blocking group at short-term folow-up, especialy at 1 week after treatment; however, these scores became better in the platelet-rich plasma group than the local blocking group during the long-term folow-up period. In addition, no statistical difference in the convenience score was found between the two groups. At the last folow-up, the recurrence rate in the platelet-rich plasma group was lower than that in the local blocking group. Both the platelet-rich plasma and local blocking injection can significantly reduce the pain of patients with ischiogluteal bursitis. Local blocking injection has better short-term effectiveness. Platelet-rich plasma injection works moderately, but its effectiveness can last for longer time, and the recurrence rate is lower.