CAJ | 학술논문

背景：目前生物相容性好、无不良反应的生物可降解材料在妇产科临床治疗和护理中应用越来越广泛，近几年在国内外发展十分迅速。目的：综述生物可降解材料在妇产科治疗中的应用。方法：由第一作者根据丰富的临床实践经验并检索PubMed、CNKI数据库，重点总结生物可降解材料在妇产科手术治疗及护理方面的应用，检索词为“degraded materials，可降解生物材料，妇科护理，手术治疗”。根据临床实际应用中出现的问题进一步展望生物可降解材料在妇产科治疗护理中的发展目标。结果与结论：生物可降解材料在生物医学材料中占有重要地位，其具有良好的生物相容性和生物安全性，聚合物和降解产物对机体不良反应小，生物力学性质、物理化学性能良好可调控，并有良好的可加工性，在妇产科治疗护理中应用广泛，如可吸收缝合线、止血材料等，取得了良好的临床效果。虽然生物材料研究取得了很大的发展，但目前应用到临床中应有很大的局限性和安全性问题。相信随着生物材料领域的进一步发展，在临床治疗和护理方面的应用前景也会越来越广阔。
배경：목전생물상용성호、무불량반응적생물가강해재료재부산과림상치료화호리중응용월래월엄범，근궤년재국내외발전십분신속。목적：종술생물가강해재료재부산과치료중적응용。방법：유제일작자근거봉부적림상실천경험병검색PubMed、CNKI수거고，중점총결생물가강해재료재부산과수술치료급호리방면적응용，검색사위“degraded materials，가강해생물재료，부과호리，수술치료”。근거림상실제응용중출현적문제진일보전망생물가강해재료재부산과치료호리중적발전목표。결과여결론：생물가강해재료재생물의학재료중점유중요지위，기구유량호적생물상용성화생물안전성，취합물화강해산물대궤체불량반응소，생물역학성질、물이화학성능량호가조공，병유량호적가가공성，재부산과치료호리중응용엄범，여가흡수봉합선、지혈재료등，취득료량호적림상효과。수연생물재료연구취득료흔대적발전，단목전응용도림상중응유흔대적국한성화안전성문제。상신수착생물재료영역적진일보발전，재림상치료화호리방면적응용전경야회월래월엄활。
BACKGROUND:Recently, the biodegradable materials with good biocompatibility and with no adverse reaction have been widely applied in the clinical treatment and care of gynecology and obstetrics. The development of the biodegradable material is very rapid. OBJECTIVE:To summarize the application of biodegradable materials in gynecology and obstetrics. METHODS: The first author searched PubMed and CNKI databases for articles related to biodegradable materials in gynecology and obstetrics using the keywords of “degraded materials, biodegradable materials, gynecological care, surgery” in Chinese and English respectively. This article has an outlook of the potential application in gynecology and obstetrics based on clinical experience. RESULTS AND CONCLUSION:Biodegradable materials with good biocompatibility and biological security play an important role in biomedical materials. Their polymers and degradation products show smal adverse reactions to the body, and have good biomechanical properties, physical and chemical properties and good workability, which have been widely used in gynecology and obstetrics, such as absorbable stylolite and tampon tape. Although we have made a great progress on the biomaterial research, it stil has the limitation and safety flaws in the clinic. As the biomaterial research is further developed, the biomaterial application prospect wil be more promising.