CAJ | 학술논문

背景：运动对于骨代谢的影响通过相关血尿生化指标的改变表现出来，以运动类型和强度影响为主。同时，这些生化指标也显示了如何标记不同个体的生理以及反映运动对骨骼的影响，可以将这些指标看成是骨生长代谢过程的一种监测。目的：从存在于血液和尿液中与骨生长代谢的相关生化指标入手，详细阐述运动对其影响，进一步讨论对机体骨形成和骨吸收的影响。方法：应用计算机检索中国学术期刊全文数据库(CNKI)和PubMed数据库中2000年1月至2014年9月关于骨代谢的文章，检索主题词为“运动；骨代谢；生化指标”；英文为“Exercise；Bone metabolism；Biochemical indicators”。初检文献236篇，根据纳入标准保留38篇进行分析、综述。结果与结论：低强度的运动对骨骼基本上起不到作用，而过度的运动对于骨骼是有害的，可以导致应力性骨折，更重要的是导致年轻女性雌激素缺乏，因而会使骨量减少。运动对骨代谢相关血尿生化指标的影响以运动类型和强度影响为主，只有把握适当的训练强度才会对骨形成和骨吸收产生积极影响，辅助骨密度、骨生物力学等指标作为制定运动处方和安排康复锻炼时的重要参考。对于运动引起骨转换的机制需要进一步结合各种通路，到细胞层面进一步讨论。
배경：운동대우골대사적영향통과상관혈뇨생화지표적개변표현출래，이운동류형화강도영향위주。동시，저사생화지표야현시료여하표기불동개체적생리이급반영운동대골격적영향，가이장저사지표간성시골생장대사과정적일충감측。목적：종존재우혈액화뇨액중여골생장대사적상관생화지표입수，상세천술운동대기영향，진일보토론대궤체골형성화골흡수적영향。방법：응용계산궤검색중국학술기간전문수거고(CNKI)화PubMed수거고중2000년1월지2014년9월관우골대사적문장，검색주제사위“운동；골대사；생화지표”；영문위“Exercise；Bone metabolism；Biochemical indicators”。초검문헌236편，근거납입표준보류38편진행분석、종술。결과여결론：저강도적운동대골격기본상기불도작용，이과도적운동대우골격시유해적，가이도치응력성골절，경중요적시도치년경녀성자격소결핍，인이회사골량감소。운동대골대사상관혈뇨생화지표적영향이운동류형화강도영향위주，지유파악괄당적훈련강도재회대골형성화골흡수산생적겁영향，보조골밀도、골생물역학등지표작위제정운동처방화안배강복단련시적중요삼고。대우운동인기골전환적궤제수요진일보결합각충통로，도세포층면진일보토론。
BACKGROUND:Based on the blood and urine biochemical changes in different intensities and types of exercise, this research describes the impact of exercise on bone metabolism. Meantime, these biochemical indexes also show a method of marking physiological differences of certain individuals, and also reflect the impact of exercise on bone. These can be regarded as a monitoring index of bone growth and metabolism. OBJECTIVE:To study exercise effect from the biochemical indicators in bone metebolism, and make a further discussion about its influence on bone formation and bone resorption. METHODS:Databases of CNKI and PubMed were retrieved by computer with key words of “exercise; bone metabolism; biochemical indicators” in Chinese and English, respectively, by screening titles and abstracts to search papers related to exercise effects on the blood and urine biochemical indicators. Totaly 236 papers were initialy found, and only 38 papers were included in result analysis. RESULTS AND CONCLUSION: Low-intensity exercise shows less effect on the bone, but excessive exercise is harmful to the bone that can cause stress fractures. What’s worse, it causes a lack of female hormone and reduce bone mass. Exercise can alter the blood and urine biochemical indicators in aspects of types of exercise and intensities. Only the exercise at appropriate intensity makes positive effects on bone formation and resorption, and assists bone mineral density and bone biomechanical indicators to develop exercise prescription and arrange rehabilitation exercises. MechanismS of bone turnover need further discussion at the celular level.