中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
46期
7406-7411
,共6页
王成伟%刘利兵%贾卫东%赵博%帕尔哈提%王雪%李璐兵%郑辉
王成偉%劉利兵%賈衛東%趙博%帕爾哈提%王雪%李璐兵%鄭輝
왕성위%류리병%가위동%조박%파이합제%왕설%리로병%정휘
组织构建%软骨组织工程%半月板损伤%膝关节%MRI%关节镜
組織構建%軟骨組織工程%半月闆損傷%膝關節%MRI%關節鏡
조직구건%연골조직공정%반월판손상%슬관절%MRI%관절경
knee joint%menisci,tibial%magnetic resonance imaging%arthroscopes
背景:MRI 以其无创及对组织的高分辨率,对损伤的高敏感性和特异性等特点已成为继膝关节疾病关节镜检查的又一重要手段。目的:通过磁共振成像和关节镜检查对膝关节半月板损伤结果进行对比,探讨膝关节半月板损伤诊断的有效评价方法。方法:回顾分析膝关节半月板损伤206 例患者的临床资料,对患膝均进行MRI检查及关节镜检查。以关节镜检查结果为金标准,计算出MRI诊断半月板损伤的灵敏度、特异度、符合率。采用χ2 结果与结论:MRI对半月板0 级、Ⅰ级损伤与关节镜诊断的符合率为97%,对半月板Ⅱ级损伤诊断的符合率为91.1%,两者差异无显著意义(P > 0.05)。MRI对半月板Ⅲ级损伤诊断的灵敏度(Sen)92.9%,特异度(Spe)94.4%,符合率为93.7%,Youden指数为87.3%,经一致性检验,两者具高度一致性(Kappa值为0.874,统计量χ检验分析来评价MRI与关节镜检查半月板损伤有无差异。采用Kappa值来检验MRI与关节镜诊断半月板损伤的一致性。 2=38.182,P=0.000)。结果提示,MRI是半月板损伤很有价值的无创性诊断方法,对于MRI表现为半月板损Ⅰ、Ⅱ级损伤的患者,应谨慎行关节镜检查;然而对于MRI表现为Ⅲ级信号的患者应尽早行关节镜检查,关节镜观察更直观,能对半月板的损伤作出准确的判断,降低漏诊率。
揹景:MRI 以其無創及對組織的高分辨率,對損傷的高敏感性和特異性等特點已成為繼膝關節疾病關節鏡檢查的又一重要手段。目的:通過磁共振成像和關節鏡檢查對膝關節半月闆損傷結果進行對比,探討膝關節半月闆損傷診斷的有效評價方法。方法:迴顧分析膝關節半月闆損傷206 例患者的臨床資料,對患膝均進行MRI檢查及關節鏡檢查。以關節鏡檢查結果為金標準,計算齣MRI診斷半月闆損傷的靈敏度、特異度、符閤率。採用χ2 結果與結論:MRI對半月闆0 級、Ⅰ級損傷與關節鏡診斷的符閤率為97%,對半月闆Ⅱ級損傷診斷的符閤率為91.1%,兩者差異無顯著意義(P > 0.05)。MRI對半月闆Ⅲ級損傷診斷的靈敏度(Sen)92.9%,特異度(Spe)94.4%,符閤率為93.7%,Youden指數為87.3%,經一緻性檢驗,兩者具高度一緻性(Kappa值為0.874,統計量χ檢驗分析來評價MRI與關節鏡檢查半月闆損傷有無差異。採用Kappa值來檢驗MRI與關節鏡診斷半月闆損傷的一緻性。 2=38.182,P=0.000)。結果提示,MRI是半月闆損傷很有價值的無創性診斷方法,對于MRI錶現為半月闆損Ⅰ、Ⅱ級損傷的患者,應謹慎行關節鏡檢查;然而對于MRI錶現為Ⅲ級信號的患者應儘早行關節鏡檢查,關節鏡觀察更直觀,能對半月闆的損傷作齣準確的判斷,降低漏診率。
배경:MRI 이기무창급대조직적고분변솔,대손상적고민감성화특이성등특점이성위계슬관절질병관절경검사적우일중요수단。목적:통과자공진성상화관절경검사대슬관절반월판손상결과진행대비,탐토슬관절반월판손상진단적유효평개방법。방법:회고분석슬관절반월판손상206 례환자적림상자료,대환슬균진행MRI검사급관절경검사。이관절경검사결과위금표준,계산출MRI진단반월판손상적령민도、특이도、부합솔。채용χ2 결과여결론:MRI대반월판0 급、Ⅰ급손상여관절경진단적부합솔위97%,대반월판Ⅱ급손상진단적부합솔위91.1%,량자차이무현저의의(P > 0.05)。MRI대반월판Ⅲ급손상진단적령민도(Sen)92.9%,특이도(Spe)94.4%,부합솔위93.7%,Youden지수위87.3%,경일치성검험,량자구고도일치성(Kappa치위0.874,통계량χ검험분석래평개MRI여관절경검사반월판손상유무차이。채용Kappa치래검험MRI여관절경진단반월판손상적일치성。 2=38.182,P=0.000)。결과제시,MRI시반월판손상흔유개치적무창성진단방법,대우MRI표현위반월판손Ⅰ、Ⅱ급손상적환자,응근신행관절경검사;연이대우MRI표현위Ⅲ급신호적환자응진조행관절경검사,관절경관찰경직관,능대반월판적손상작출준학적판단,강저루진솔。
BACKGROUND:MRI characterized as non-invasion, high resolution, high sensitivity and specificity to injury has become another important means for diagnosis of knee joint disease folowing the arthroscopy. OBJECTIVE: To explore the effective evaluation on the knee meniscus injury diagnosis, by comparing the results of MRI and arthroscopy of the knee meniscus. METHODS: Clinical data of 206 patients with meniscus injury were retrospectively analyzed. Every case was subjected to MRI and the arthroscopy. The findings of arthroscopy were considered as the golden standard. Then, the sensitivity, specificity and coincidence rate of MRI in the diagnosis of meniscus injury were calculated. The chi-square analysis was used to evaluate the MRI and arthroscopy in the diagnosis of meniscus injury. The Kappa values were used to test the consistency of MRI with arthroscopy in the diagnosis of meniscus injury. RESULTS AND CONCLUSION:For levels 0 and I meniscus injury, the coincidence rate of MRI was 97%; for level II meniscus injury, the coincidence rate of MRI was 91.1%, and there was no significant difference (P > 0.05). For level III meniscus injury, the sensitivity, specificity, concordance rate and Youden index of MRI were 92.9%, 94.4%, 93.7% and 87.3%, respectively. By the consistency checking, the value of Kappa was 0.874 and χ2 so there was a high consistency checking between the data of MRI and arthroscopy (P=0.000). MRI is a noninvasive diagnostic method for meniscus injury. For patients with levels I and II meniscus injury on MRI, arthroscopy should be cautiously adopted; however, for patients with level III meniscus injury on MRI, arthroscopy should be done as early as possible. Arthroscopic observation is more intuitive that enables to make accurate judgments of meniscus injury to reduce the rate of misdiagnosis.