CAJ | 학술논문

目的：观察三磷酸腺苷二钠氯化镁治疗支气管肺炎所致心肌受损的临床疗效。方法将172例支气管肺炎并发心肌受损患儿随机分为观察组78例和对照组94例,两组均抗感染及对症支持等常规治疗,观察组用三磷酸腺苷二钠氯化镁营养心肌,对照组用二磷酸果糖营养心肌,疗程均为1周。比较两组患儿治疗前后CK-MB及cTnl的变化。结果治疗1周后,CK-MB和cTnl的检测值较治疗前均降低,但观察组降低更显著(P<0．01)；CK-MB和cTnl的阳性率较治疗前均降低,两组相比,CK-MB的阳性率差异无统计学意义(P>0．05),而cTnl的阳性率差异有统计学意义(P<0．05)。结论三磷酸腺苷二钠氯化镁治疗支气管肺炎所致心肌受损,疗效好。
목적：관찰삼린산선감이납록화미치료지기관폐염소치심기수손적림상료효。방법장172례지기관폐염병발심기수손환인수궤분위관찰조78례화대조조94례,량조균항감염급대증지지등상규치료,관찰조용삼린산선감이납록화미영양심기,대조조용이린산과당영양심기,료정균위1주。비교량조환인치료전후CK-MB급cTnl적변화。결과치료1주후,CK-MB화cTnl적검측치교치료전균강저,단관찰조강저경현저(P<0．01)；CK-MB화cTnl적양성솔교치료전균강저,량조상비,CK-MB적양성솔차이무통계학의의(P>0．05),이cTnl적양성솔차이유통계학의의(P<0．05)。결론삼린산선감이납록화미치료지기관폐염소치심기수손,료효호。
Objective To observe the therapeutic effect of adenosine disodium triphosphate and magnesium chloride in the treatment of children with myocardial injury induced by bronchopneumonia. Methods 172 children with myocardial injury induced by bronchopneumonia were randomly divided into two groups. All children were given antibiotics and the conventional treatment. 78 cases as the experimental group were given adenosine disodium triphos- phate and magnesium chloride for injection additionally. 94 cases as the control group were given sodium fructose diphosphate for injection additionally. The data of CK-MB and cTnl were compared between the two groups after one week. Results 1 week after the treatment, the value of CK-MB and cTnl reduced in the two groups, and the de-crease was more pronounced in the experimental group than in the control group (P<0. 01). The positive rate of CK-MB and cTnl reduced in the two groups, but there was no significant difference in the positive rate of CK-MB between the two groups (P>0. 05). The positive rate of cTnl was obviously lower in the experimental group than in the con-trol group (P<0. 05). Conclusion The treatment of adenosine disodium triphosphate and magnesium chloride in children with myocardial injury induced by bronchopneumonia is safe and effective.