CAJ | 학술논문

胃癌（ Gastric carcinoma ，GC）的发病率居全世界恶性肿瘤的第四位，死亡率居第二位。尽管胃癌的发病率在过去的几十年里有所下降，但它仍然是一个严重危害健康的问题。肿瘤微环境在肿瘤的发生和进展中有重要作用，主要包括肿瘤相关的巨噬细胞、淋巴细胞、癌相关成纤维细胞、血管生成因子、细胞因子、肿瘤微环境以及它们作用机制的信号趋化因子等。本文就肿瘤微环境与胃癌相关性的研究进展综述如下。
위암（ Gastric carcinoma ，GC）적발병솔거전세계악성종류적제사위，사망솔거제이위。진관위암적발병솔재과거적궤십년리유소하강，단타잉연시일개엄중위해건강적문제。종류미배경재종류적발생화진전중유중요작용，주요포괄종류상관적거서세포、림파세포、암상관성섬유세포、혈관생성인자、세포인자、종류미배경이급타문작용궤제적신호추화인자등。본문취종류미배경여위암상관성적연구진전종술여하。
Gastric cancer is the fourth malignancies and the second cancer -related mortality rate in the world.Although the incidence of gastric cancer has declined in the past few decades ,it is still a serious health problem.Tumor microenvironment plays an important role in tumorigenesis and progression .The main components of gastric cancer include tumor associated macrophages、lymphocytes、cancer-associated fibroblasts、angiogenesis factors,cytokines,gastric microenvironment and the mechanism of action of chemokines .In this review,the corre-lation between tumor microenvironment and GC is discussed .