肿瘤基础与临床
腫瘤基礎與臨床
종류기출여림상
JOURNAL OF BASIC AND CLINICAL ONCOLOGY
2014年
6期
487-488
,共2页
非小细胞肺癌%培美曲塞%顺铂%卡铂
非小細胞肺癌%培美麯塞%順鉑%卡鉑
비소세포폐암%배미곡새%순박%잡박
non-small cell lung cancer%pemetrexed%cisplatin%carboplatin
目的:分析培美曲塞联合顺铂或卡铂治疗晚期非小细胞肺癌( NSCLC)的疗效及毒副反应。方法41例晚期NSCLC患者接受培美曲塞联合顺铂或卡铂治疗方案。结果41例晚期NSCLC患者中,有效率为26.8%(11/41),疾病控制率为63.4%(26/41);治疗后有25例患者(61.0%)KPS评分提高;毒副反应主要为骨髓抑制和胃肠道反应。结论培美曲塞联合顺铂或卡铂治疗晚期NSCLC安全有效。
目的:分析培美麯塞聯閤順鉑或卡鉑治療晚期非小細胞肺癌( NSCLC)的療效及毒副反應。方法41例晚期NSCLC患者接受培美麯塞聯閤順鉑或卡鉑治療方案。結果41例晚期NSCLC患者中,有效率為26.8%(11/41),疾病控製率為63.4%(26/41);治療後有25例患者(61.0%)KPS評分提高;毒副反應主要為骨髓抑製和胃腸道反應。結論培美麯塞聯閤順鉑或卡鉑治療晚期NSCLC安全有效。
목적:분석배미곡새연합순박혹잡박치료만기비소세포폐암( NSCLC)적료효급독부반응。방법41례만기NSCLC환자접수배미곡새연합순박혹잡박치료방안。결과41례만기NSCLC환자중,유효솔위26.8%(11/41),질병공제솔위63.4%(26/41);치료후유25례환자(61.0%)KPS평분제고;독부반응주요위골수억제화위장도반응。결론배미곡새연합순박혹잡박치료만기NSCLC안전유효。
Objective To evaluate the efficacy and toxicities of pemetrexed plus cisplatin or carboplatin in the treatment of patients with advanced non-small cell lung cancer( NSCLC). Methods Forty-one patients with ad-vanced NSCLC received pemetrexed plus cisplatin or carboplatin. Results Among the 41 patients advanced NSCLC,the response rate was 26. 8%(11/41),the disease control rate was 63. 4%(26/41);the KPS scores in the 25 patients(61. 0%)were increased. The common toxicities were bone marrow depression and gastrointestinal reaction. Conclusion Pemetrexed plus cisplatin or carboplatin is a safe and effective regimen for the patients with advanced NSCLC.