大连大学学报
大連大學學報
대련대학학보
JOURNAL OF DALIAN UNIVERSITY
2014年
6期
62-68
,共7页
曹洪玉%张莹莹%唐乾%郑学仿
曹洪玉%張瑩瑩%唐乾%鄭學倣
조홍옥%장형형%당건%정학방
蛋白质%表面活性剂%相互作用
蛋白質%錶麵活性劑%相互作用
단백질%표면활성제%상호작용
protein%surfactant%interaction
表面活性剂和蛋白质作用的方式与表面活性剂的种类、结构、浓度和其理化性质有关。本文系统地总结了多种类型表面活性剂(阴离子型、阳离子型、两性离子型、非离子型、氟表面活性剂及 Gemini 表面活性剂)的结构特点,以蛋白质-表面活性剂相互作用的物理化学特征为出发点,综述了该体系相互作用的最新研究成果及进展,包括二者作用时所形成的复合物的结构理论,复合物的吸附机理及其作用过程中蛋白质结构的变化;结合本课题组的工作总结分析了蛋白质分别与各类表面活性剂相互作用过程中作用力特征、相行为、作用机理及应用。
錶麵活性劑和蛋白質作用的方式與錶麵活性劑的種類、結構、濃度和其理化性質有關。本文繫統地總結瞭多種類型錶麵活性劑(陰離子型、暘離子型、兩性離子型、非離子型、氟錶麵活性劑及 Gemini 錶麵活性劑)的結構特點,以蛋白質-錶麵活性劑相互作用的物理化學特徵為齣髮點,綜述瞭該體繫相互作用的最新研究成果及進展,包括二者作用時所形成的複閤物的結構理論,複閤物的吸附機理及其作用過程中蛋白質結構的變化;結閤本課題組的工作總結分析瞭蛋白質分彆與各類錶麵活性劑相互作用過程中作用力特徵、相行為、作用機理及應用。
표면활성제화단백질작용적방식여표면활성제적충류、결구、농도화기이화성질유관。본문계통지총결료다충류형표면활성제(음리자형、양리자형、량성리자형、비리자형、불표면활성제급 Gemini 표면활성제)적결구특점,이단백질-표면활성제상호작용적물이화학특정위출발점,종술료해체계상호작용적최신연구성과급진전,포괄이자작용시소형성적복합물적결구이론,복합물적흡부궤리급기작용과정중단백질결구적변화;결합본과제조적공작총결분석료단백질분별여각류표면활성제상호작용과정중작용력특정、상행위、작용궤리급응용。
Surfactants interact with proteins in multifarious ways which depend on surfactant types, concentration, structure, and physical-chemical properties. To obtain a global overview of this process, the physicochemical properties of the interaction was began with introducing between proteins and surfactants, the recent research including the structural properties of protein-surfactant complex, the adsorption mechanisms of the complex, as well as the structural changes of proteins induced by surfactants. Then different phase behaviors and interaction mechanisms of proteins interaction were expounded with five different classes of surfactants, including anionic surfactants, cationic surfactants, zwitterionic surfactants, non-ionic surfactants, fluorine and Gemini surfactants. Recent research scope and current situation in every field had also been reviewed. Our results and methods in studying protein-surfactant interaction were systematically summarized in the suitable part.