CAJ | 학술논문

目的：分析新生儿血培养阳性标本中各病原菌分布情况及主要病原菌的耐药特点。方法采用BACTEC-9120全自动血培养仪，BD专用儿童体液培养瓶培养血液样本，分离所得菌株采用VITEK32自动微生物分析仪进行细菌鉴定和药物敏感试验。结果血培养阳性结果以革兰氏阳性菌为主，占74.8％，其中以表皮葡萄球菌为主；革兰氏阴性杆菌占24.2％。革兰氏阳性菌对万古霉素均敏感；革兰氏阴性杆菌对碳青霉烯类抗菌药物高度敏感。结论病原菌耐药性检测对血液感染新生儿非常重要，根据药敏结果选用敏感抗菌药物，可提高临床治疗效果，减少细菌耐药性的产生。
목적：분석신생인혈배양양성표본중각병원균분포정황급주요병원균적내약특점。방법채용BACTEC-9120전자동혈배양의，BD전용인동체액배양병배양혈액양본，분리소득균주채용VITEK32자동미생물분석의진행세균감정화약물민감시험。결과혈배양양성결과이혁란씨양성균위주，점74.8％，기중이표피포도구균위주；혁란씨음성간균점24.2％。혁란씨양성균대만고매소균민감；혁란씨음성간균대탄청매희류항균약물고도민감。결론병원균내약성검측대혈액감염신생인비상중요，근거약민결과선용민감항균약물，가제고림상치료효과，감소세균내약성적산생。
Objective To investigate the distribution and antibiotic resistance of pathogens isolated from blood specimens of neonates .Methods The BACTEC-9120 automatic blood culture instrument and BD special children fluid culture bottle were used to culture the blood of neonates .Isolated strains were identified ,and their drug sensitivity tests were completed by VITEK 32 system .Results The results showed that Gram-positive cocci accounted for 74.8% ,in which Staphylococcus epidermidis ac- counted mainly ,and gram-negative bacteria accounted for 24.2% .gram-positive cocci were sensitive to vancomycin ,and gram- negative bacteria were sensitive to carbapenem .Conclusion Pathogen drug resistance detection is very important for neonates with blood infection .Choosing sensitive antibiotic drugs according to the result of drug susceptibility can improve the clinical curative effect and reduce the antibiotic resistance .