安徽卫生职业技术学院学报
安徽衛生職業技術學院學報
안휘위생직업기술학원학보
JOURNAL OF ANHUI HEALTH VOCATIONAL & TECHNICAL COLLEGE
2014年
6期
43-44
,共2页
地佐辛%硬膜外麻醉%胆囊切除术%内脏牵拉反射
地佐辛%硬膜外痳醉%膽囊切除術%內髒牽拉反射
지좌신%경막외마취%담낭절제술%내장견랍반사
Dezocine%Epidural anesthesia%Cholecystectomy%The visceral traction reaction
目的：观察地佐辛对硬膜外麻醉下经腹胆囊切除术内脏牵拉反应的疗效。方法：选择60例欲行经腹胆囊切除术的患者，ASAⅠ~Ⅱ级，拟施连续硬膜外麻醉，随机分为地佐辛组（D组）和芬太尼组（F组），各30例。两组均在切皮前2min静脉分别给以地佐辛0.1mg/kg，芬太尼1~2ug/kg，常规检测，并对牵拉反应抑制效果进行评估，观察患者恶心、呕吐、疼痛等发生率。观察记录点分别为术前（T1），切皮后5min（T2），切皮后15min（T3），牵拉胆囊时（T4），胆囊切除后（T5）。结果：血流动力学比较，D组比F组在BP、HR更好地维持平稳，差异有统计学意义（P<0.05）；胆囊牵拉反应，D组少于F组，差异有统计学意义（P<0.05）。结论：地佐辛可以提供良好的镇痛效果，在内脏牵拉方面也有很大的优势，可以减少恶心呕吐的发生。
目的：觀察地佐辛對硬膜外痳醉下經腹膽囊切除術內髒牽拉反應的療效。方法：選擇60例欲行經腹膽囊切除術的患者，ASAⅠ~Ⅱ級，擬施連續硬膜外痳醉，隨機分為地佐辛組（D組）和芬太尼組（F組），各30例。兩組均在切皮前2min靜脈分彆給以地佐辛0.1mg/kg，芬太尼1~2ug/kg，常規檢測，併對牽拉反應抑製效果進行評估，觀察患者噁心、嘔吐、疼痛等髮生率。觀察記錄點分彆為術前（T1），切皮後5min（T2），切皮後15min（T3），牽拉膽囊時（T4），膽囊切除後（T5）。結果：血流動力學比較，D組比F組在BP、HR更好地維持平穩，差異有統計學意義（P<0.05）；膽囊牽拉反應，D組少于F組，差異有統計學意義（P<0.05）。結論：地佐辛可以提供良好的鎮痛效果，在內髒牽拉方麵也有很大的優勢，可以減少噁心嘔吐的髮生。
목적：관찰지좌신대경막외마취하경복담낭절제술내장견랍반응적료효。방법：선택60례욕행경복담낭절제술적환자，ASAⅠ~Ⅱ급，의시련속경막외마취，수궤분위지좌신조（D조）화분태니조（F조），각30례。량조균재절피전2min정맥분별급이지좌신0.1mg/kg，분태니1~2ug/kg，상규검측，병대견랍반응억제효과진행평고，관찰환자악심、구토、동통등발생솔。관찰기록점분별위술전（T1），절피후5min（T2），절피후15min（T3），견랍담낭시（T4），담낭절제후（T5）。결과：혈류동역학비교，D조비F조재BP、HR경호지유지평은，차이유통계학의의（P<0.05）；담낭견랍반응，D조소우F조，차이유통계학의의（P<0.05）。결론：지좌신가이제공량호적진통효과，재내장견랍방면야유흔대적우세，가이감소악심구토적발생。
Objective:To observe the curative effect of dezocine on the visceral traction reaction in abdominal cholecystectomy under epidural anesthesia Methods:Select 60 patients ,ASAⅠ-Ⅱ grade, undergoing abdominal cholecystectomy in continuous epidural anesthesia. They were randomly divided into two groups, respectively named dezocine group (group D) and fentanyl group (group F), 30 cases in each. The two groups were given 2 min intra-venously before skin incision respectively dezocine 0.1mg/kg and fentanyl 1-2ug/kg, and inhale oxygen by mask, monitored conventionally. The inhibition effect of the visceral traction reaction was evaluated, and observe the inci-dence of pain, nausea and vomiting. Time observation points were preoperative (T1), 5min after skin incision (T2), 15min after skin incision (T3), pulling gallbladder (T4),after cholecystectomy (T5). Results:Compared with group F , BP and HR in group D remained more stable, with statistical significance ( P<0.05 );In the aspect of gallbladder traction reaction, the incident in the group D was lower than that in the group F, and there was statistically significant ( P<0.05 ). Conclusion:Dezocine can provide a good analgesic effect ,also have a lot of advantages in the aspect of the visceral trac-tion, so it can reduce the incidence of nausea and vomiting. But the optimal dose and the optimal time tests are needed in the further study to prove the best effect.
