CAJ | 학술논문

目的：研究吸烟对男性精子形态、精子DNA完整率[用精子DNA断裂指数（ DFI）表示]及顶体完整率的影响。方法回顾性分析来该中心就诊的1500例男性患者（1300例吸烟者及200例未吸烟者），按每天吸烟量分为A1组500例，＞20支／d；A2组600例，10～20支／d；A3组200例，1～9支／d。 B组200例，0支／d，作为对照组。结果精子正常形态随着每天吸烟量的增加而下降，各组间两两比较差异有统计学意义（ P＜0．05）。精子DNA完整率随着吸烟量的上升而降低（ DFI升高），各组间两两比较差异有统计学意义（ P＜0．05）。精子顶体完整率随吸烟量上升而下降，各组间两两比较差异有统计学意义（ P＜0．05）。结论随着每天吸烟量增加精子正常形态、精子DNA完整率及精子顶体完整率均降低，不利于男性生殖健康。
목적：연구흡연대남성정자형태、정자DNA완정솔[용정자DNA단렬지수（ DFI）표시]급정체완정솔적영향。방법회고성분석래해중심취진적1500례남성환자（1300례흡연자급200례미흡연자），안매천흡연량분위A1조500례，＞20지／d；A2조600례，10～20지／d；A3조200례，1～9지／d。 B조200례，0지／d，작위대조조。결과정자정상형태수착매천흡연량적증가이하강，각조간량량비교차이유통계학의의（ P＜0．05）。정자DNA완정솔수착흡연량적상승이강저（ DFI승고），각조간량량비교차이유통계학의의（ P＜0．05）。정자정체완정솔수흡연량상승이하강，각조간량량비교차이유통계학의의（ P＜0．05）。결론수착매천흡연량증가정자정상형태、정자DNA완정솔급정자정체완정솔균강저，불리우남성생식건강。
Objective To study the effect of smoking on male sperm morphology ,sperm DNA integrity rate [ DNA fragmentation index ( DFI) was used for the evaluating ] and acrosome integrity rate .Methods A retrospective analysis was performed on 1 500 male patients come to our center for treatment ( 1 300 smokers and 200 non-smok-ers).According to the daily smoking quantity the patients were divided into A 1 group(500 cases):>20/day, A2 group(600 cases):10~20/day, A3 group(200 cases):1~9/day;and group B(200 cases):0/day(as the control group) .Results The normal morphology rate of sperm decreased with the increase of daily smoking quantity , the pair comparison showed a significant differences between groups ( P<0.05 ); the rate of sperm DNA integrity de-creased with the rise of smoking ( DFI will be increase ) , the pair comparison showed a significant differences between groups(P<0.05);the sperm acrosome integrity rate decreased with the increase of smoking quantity , the pair com-parison showed a significant differences between groups ( P<0.05 ) .Conclusion With the increase of daily smoking quantity the rate of normal sperm morphology , sperm DNA integrity rate and sperm acrosome integrity rate are re-duced,and is not good for male reproductive health .