CAJ | 학술논문

目的：总结食管高级别上皮内瘤变诊断及治疗方法。方法回顾性分析28例食管高别上皮内瘤变患者的临床资料。结果接受内镜粘膜下剥离术手术治疗的28例患者中,16例(57%)术后病理证实维持高级别上皮内瘤变的诊断,其余12例(43%)术后则诊断为食管癌。结论内镜下病理检查诊断食管高级别上皮内瘤变准确率57%，内镜下活检不能作为高级别上皮内瘤变的确诊依据,应积极随访甚至手术干预。内镜粘膜下剥离术为治疗食管高级别上皮内瘤变的有效方法。
목적：총결식관고급별상피내류변진단급치료방법。방법회고성분석28례식관고별상피내류변환자적림상자료。결과접수내경점막하박리술수술치료적28례환자중,16례(57%)술후병리증실유지고급별상피내류변적진단,기여12례(43%)술후칙진단위식관암。결론내경하병리검사진단식관고급별상피내류변준학솔57%，내경하활검불능작위고급별상피내류변적학진의거,응적겁수방심지수술간예。내경점막하박리술위치료식관고급별상피내류변적유효방법。
Objective To summarize methods for the diagnosis and treatment of esophageal intraepithelial neoplasia on high grade. Methods The clinical data of 28 cases with esophageal intraepithelial neoplasia on high grade were analyzed retrospectively. Results Among 28 patients suffering from Endoscopic Submucosal Dissection (ESD),pathologies of all patients were as follows: 16 cases (57 %) intraepithelial neoplasia on high grade, 12 cases(43 %) esophageal carcinoma. Conclusions The accuracy of endoscopic pathologic examination in the diagnosis of esophageal intraepithelial neoplasia on high grade was 57%.Endoscopic biopsy did not identify esophageal intraepithelial neoplasia on high grade and actively follow-up or surgical intervention were must. ESD was effective method for treatment of esophageal intraepithelial neoplasia on high grade.