首都医药
首都醫藥
수도의약
CAPITAL MEDICINE
2014年
24期
44-45,46
,共3页
翟丽佳%闵凤玲%周玮%高小惠%张丽娜
翟麗佳%閔鳳玲%週瑋%高小惠%張麗娜
적려가%민봉령%주위%고소혜%장려나
眼%黏膜相关淋巴瘤%骨髓侵犯%治疗
眼%黏膜相關淋巴瘤%骨髓侵犯%治療
안%점막상관림파류%골수침범%치료
eyes%MALT%bone marrow involvement%treatment
目的:观察眼附属器黏膜相关淋巴瘤的临床特点。方法报告1例双眼同时起病的眼附属器黏膜相关样淋巴组织(MALT)结外边缘区B细胞淋巴瘤(OAML)并骨髓侵犯一例,结合文献对该类型淋巴瘤病因、临床表现、免疫组化、分子生物学改变、治疗进行探讨。结果OAML大部分为局限性病变,单侧多见,晚期播散型少见。结论 OAML为惰性过程,相关至死率低,对于ⅠE可给予放疗,加用免疫化学治疗可降低复发,对于ⅣE期患者需全身化疗,总体预后良好。
目的:觀察眼附屬器黏膜相關淋巴瘤的臨床特點。方法報告1例雙眼同時起病的眼附屬器黏膜相關樣淋巴組織(MALT)結外邊緣區B細胞淋巴瘤(OAML)併骨髓侵犯一例,結閤文獻對該類型淋巴瘤病因、臨床錶現、免疫組化、分子生物學改變、治療進行探討。結果OAML大部分為跼限性病變,單側多見,晚期播散型少見。結論 OAML為惰性過程,相關至死率低,對于ⅠE可給予放療,加用免疫化學治療可降低複髮,對于ⅣE期患者需全身化療,總體預後良好。
목적:관찰안부속기점막상관림파류적림상특점。방법보고1례쌍안동시기병적안부속기점막상관양림파조직(MALT)결외변연구B세포림파류(OAML)병골수침범일례,결합문헌대해류형림파류병인、림상표현、면역조화、분자생물학개변、치료진행탐토。결과OAML대부분위국한성병변,단측다견,만기파산형소견。결론 OAML위타성과정,상관지사솔저,대우ⅠE가급여방료,가용면역화학치료가강저복발,대우ⅣE기환자수전신화료,총체예후량호。
Objective To observe the clinical features of mucosa-associated lymphoma in ocular adnexal. Methods Report a medical case of illness, in which MALT in ocular adnexal is affected by OAML, together with bone marrow involvement. Analysis is given with research reference, on the cause of this type of lymphoma, clinical symptom, immunohistochemistry, molecular biological changes, and its treatment. Results Most OAML are partial pathological changes, more often unilateral cases, seldom lateral period dissemination cases. Conclusions OAML is a process of inertia, with low death rate. Radiotherapy, plus immunochemotherapy, is suitable for IE cases, while whole body radiotherapy is for IVE cases.