中国血液流变学杂志
中國血液流變學雜誌
중국혈액류변학잡지
CHINESE JOURNAL OF HEMORHEOLOGY
2014年
2期
268-271
,共4页
腮腺癌%三维适形放疗%调强放疗
腮腺癌%三維適形放療%調彊放療
시선암%삼유괄형방료%조강방료
parotid cancer%3DCRT%IMRT
目的：通过比较腮腺癌术后常规放疗（CRT）、三维适形放疗（3DCRT）与调强放疗（IMRT）靶区剂量分布的均匀性、适形性和靶区剂量情况，以及各危及器官受照体积、剂量情况，探讨I M RT用于腮腺癌术后治疗的可行性。方法选取10例腮腺癌术后患者，放疗前行CT扫描并勾画靶区。在三维治疗计划系统（TPS）上分别对每例患者行二维电子线+X线混合照射（X+E)、3DCRT、IMRT设计计划，分析腮腺癌术后患者分别运用三种放疗方法的剂量体积直方图（DVH），比较患者的靶区适形度、均匀指数，靶区剂量、靶区覆盖情况及各个危及器官的受照射剂量，评价腮腺癌术后IMRT较3DCRT的剂量学优势。结果在靶区覆盖方面，3DCRT的V95%和适形指数（CI）（96.5%和0.76）明显优于二维照射（77.7%和0.49）（P均＜0.05），但劣于IMRT（99.1%和0.84）（P均＜0.05）。结论IMRT技术无论从靶区覆盖还是对正常器官保护方面均优于CRT及3DCRT。
目的：通過比較腮腺癌術後常規放療（CRT）、三維適形放療（3DCRT）與調彊放療（IMRT）靶區劑量分佈的均勻性、適形性和靶區劑量情況，以及各危及器官受照體積、劑量情況，探討I M RT用于腮腺癌術後治療的可行性。方法選取10例腮腺癌術後患者，放療前行CT掃描併勾畫靶區。在三維治療計劃繫統（TPS）上分彆對每例患者行二維電子線+X線混閤照射（X+E)、3DCRT、IMRT設計計劃，分析腮腺癌術後患者分彆運用三種放療方法的劑量體積直方圖（DVH），比較患者的靶區適形度、均勻指數，靶區劑量、靶區覆蓋情況及各箇危及器官的受照射劑量，評價腮腺癌術後IMRT較3DCRT的劑量學優勢。結果在靶區覆蓋方麵，3DCRT的V95%和適形指數（CI）（96.5%和0.76）明顯優于二維照射（77.7%和0.49）（P均＜0.05），但劣于IMRT（99.1%和0.84）（P均＜0.05）。結論IMRT技術無論從靶區覆蓋還是對正常器官保護方麵均優于CRT及3DCRT。
목적：통과비교시선암술후상규방료（CRT）、삼유괄형방료（3DCRT）여조강방료（IMRT）파구제량분포적균균성、괄형성화파구제량정황，이급각위급기관수조체적、제량정황，탐토I M RT용우시선암술후치료적가행성。방법선취10례시선암술후환자，방료전행CT소묘병구화파구。재삼유치료계화계통（TPS）상분별대매례환자행이유전자선+X선혼합조사（X+E)、3DCRT、IMRT설계계화，분석시선암술후환자분별운용삼충방료방법적제량체적직방도（DVH），비교환자적파구괄형도、균균지수，파구제량、파구복개정황급각개위급기관적수조사제량，평개시선암술후IMRT교3DCRT적제량학우세。결과재파구복개방면，3DCRT적V95%화괄형지수（CI）（96.5%화0.76）명현우우이유조사（77.7%화0.49）（P균＜0.05），단렬우IMRT（99.1%화0.84）（P균＜0.05）。결론IMRT기술무론종파구복개환시대정상기관보호방면균우우CRT급3DCRT。
Objective To compare the homogeneity and conformity of dose distribution in the target, the treatment period of patients and the dose to the organs at risk among conventional radiation therapy (CRT), three-dimensional conformal radiation therapy (3DCRT) and intensity modulated radiation therapy (IMRT), and then to evaluate the clinical value of IMRT for postoperative irradiation of parotid cancer. Methods Ten patients with parotid cancer postoperative were selected. Before the treatment, computed tomography scan image were transferred to an IMRT planning system. To design the unilateral field with mixture of 12 MV photon and electron beams (X+E), 3DCRT, IMRT plans respectively for each patient. Through the analysis of the dose volume histogram (DVH) by single lesions of the patients, using three kinds of radiation methods, three groups were compared for conformal radiotherapy target area conformal degree, uniform index area, target area dose and each endanger organ by irradiation dose, to investigate the dosimetry advantages of IMRT. Results Compared with conventional planning, the CRT, 3DCRT and IMRT plans produced adequate target coverage, and the comformity index (CI) showed 3DCRT plans (0.76) and CRT plans (0.49) produced poorer target coverage than IMRT (0.84). Conclusion For postoperative irradiation of parotid cancer, IMRT planning techniques generated better target dose-coverage, without compromising the dose-sparing advantages of important structures.
