CAJ | 학술논문

目的探讨惊恐障碍（PD）患者催眠状态前后的事件相关电位P300及脑电图（EEG）的变化。方法记录29例PD患者催眠前和进入催眠状态后的P300和EEG，进行自身对照研究。结果患者进入催眠状态后，P300波幅下降[催眠前后的靶波幅P3分别为（6.5±2.1）μV和（3.1±1.9）μV；催眠前后的非靶波幅P2分别为（4.2±2．1）μV和（2.0±1.7）μV，P均＜0.05]。EEG背景节律α波频率，在催眠前为（10.3±0.8）Hz，催眠后为（8.9±0.9）Hz （P＜0.05）。结论 PD患者催眠状态下的P300和EEG变化特点有助于临床判断。
목적탐토량공장애（PD）환자최면상태전후적사건상관전위P300급뇌전도（EEG）적변화。방법기록29례PD환자최면전화진입최면상태후적P300화EEG，진행자신대조연구。결과환자진입최면상태후，P300파폭하강[최면전후적파파폭P3분별위（6.5±2.1）μV화（3.1±1.9）μV；최면전후적비파파폭P2분별위（4.2±2．1）μV화（2.0±1.7）μV，P균＜0.05]。EEG배경절률α파빈솔，재최면전위（10.3±0.8）Hz，최면후위（8.9±0.9）Hz （P＜0.05）。결론 PD환자최면상태하적P300화EEG변화특점유조우림상판단。
Objective To observe the changes of event related potential P 300 and EEG in panic disorder ( PD) patients before and after hypnotic state . Methods Before and after hypnosis , P300 and EEG were recorded and compared in 29 PD patients. Results Compared with that before hypnosis state , P300 amplitude [(6.5 ±2.1) μV vs.(3.1 ±1.9) μV, P<0.05] and non-target P2 amplitude [(4.2 ±2.1) μV vs.(2.0 ±1.7) μV, P<0.05] decreased significantly . Significantly slower background rhythm of alpha wave was observed in hypnotic state [(10.3 ±0.8)Hz vs.(8.9 ±0.9)Hz, P<0.05]. Conclusion In patients with panic disorder, the changes of P300 and EEG in hypnotic state are helpful for clinical diagnosis .